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RIP1在细胞程序性死亡中作用的研究进展 被引量：2

Role of RIP1 in programmed cell death
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摘要 近期研究发现受体相互作用蛋白(receptor-interacting protein,RIP)是细胞生存和死亡的重要交叉点,在细胞的凋亡与存活、程序性坏死等过程中发挥着关键性的作用。RIP1为RIP家族中的第一个成员,是一种重要的细胞信号转导调控分子。RIP1的结构与生物学功能及在细胞程序性死亡中的作用具有重要意义。 Recent studies showed that RIP kinase functions as the crossroads for cell survival, death, apoptosis and necroptosis. Receptor interacting protein 1 （RIP1）, the first member of the RIP family, plays a key role in regulation of cell signaling transduction. It is important to elucidate the structure, biological function and the role of RIP1 in programmed cell death.
作者 章余妹 张林杰
机构地区 安徽省肿瘤医院肿瘤内科 安徽医科大学免疫学教研室
出处 《国际病理科学与临床杂志》 CAS 2013年第5期453-457,共5页 Journal of International Pathology and Clinical Medicine
基金 国家自然科学基金(81071809) 安徽省高等学校省级自然科学研究项目(KJ2011A167)~~
关键词 受体相互作用蛋白1 凋亡 程序性坏死 receptor interacting protein 1 apoptosis programmed necrosis
分类号 R363 [医药卫生—病理学]
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共引文献10

同被引文献27

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国际病理科学与临床杂志
2013年 第5期

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