冠脉慢血流患者脑循环的探讨

The evaluation of cereberal circulation in patients with slow coronary flow

目的 探讨冠状动脉慢血流患者脑循环是否受到损害.方法 选取60例因胸痛症状住院并行冠脉造影检查结果示冠状动脉血流缓慢,但管腔无明显狭窄的患者为研究组;同期因胸痛症状入院并行冠脉造影检查为正常冠脉的55例患者为对照组,两组患者冠脉造影术后24小时通过经颅多普勒彩超测量大脑中动脉、基底动脉血流速度,比较两组病例大脑中动脉、基底动脉血流是否存在差异.结果 冠脉慢血流患者两侧大脑中动脉、基底动脉收缩期、舒张末期及平均血流速度明显慢于对照组.结论 冠脉慢血流患者脑循环也受到损害,慢血流现象可能是体循环系统受损的局部表现.

Objective To investigate whether cerebral flow velocity is impaired in patients with slow coronary flow. Methods A total of 60 patients suffering from chest pain with angiographically proven solw coronary flow（SCF） and 55 age- and sex-matched control patients, who also suffering from chest pain and underwent diagnostic coronary angiography and found to have normal coronary epicardial coronary an- giogram constituted the SCF and control groups, respctively. The average peak systolic and diastolic and mean flow velocities of the middle cerebral artery were measured, and recorded in both groups by transcra- nial Doppler ultrasonography 24 hours after the angiography. Results Both right and left middle cerebral and basilar artery peak systolic, end diastolic and mean flow velocities were significantily lower in patients with SCF than thoses with normal coronary flow. ConclusionThe cerebral blood flow velocity is significant- ly lower in patients with SCF,SCF phenomenon may reflect a part of impaired systemic circulation.