摘要
药品不良反应(adversedrugreaction,ADR)是指合格药品在正常用法、用量下出现的与用药目的无关的非故意导致的有害反应。皮肤是ADR最常见的靶器官之一,药疹是最常见的ADR,其在住院病例中的发生率〉2%。重型史蒂文斯.约翰逊综合征(Steven-Johnson-Syndrome,SJS)及中毒性表皮坏死松解症(TEN),统称SJS—TEN,是一组危及患者生命的重症药疹,死亡率高、危害大,
出处
《药物流行病学杂志》
CAS
2013年第11期600-602,共3页
Chinese Journal of Pharmacoepidemiology
参考文献13
-
1Fiszenson- Albala F, Auzerie V, Mahe E,et al. A 6- monthprospectivesurvey of cutaneous drug reactions in a hospitalsetting[ J] . Br J Dermatol,2003 ,149( 5) :1018- 1022.
-
2朱学骏,王宝玺,孙建方,等.皮肤病学[M].第2版,北京:北京大学医学出版社,2011.1476.
-
3Chave TA,. Mortimer NJ,Sladden MJ,et al. Toxic epider-mal necrolysis : current evidence, practical management andfuture directions [ J ]. The British Journal of Dermatology,2005,153(2) ;241-253.
-
4Petkov T, Pehlivanov G, Grozdev I,et al. Toxic epidermalnecrolysis as a dermatological manifestation of drug hyper-sensitivity syndrome[ J]. European Journal of Dermatology,2007,17(5) :422427.
-
5Viard I,Wehrli P,Bullani R, et al. Inhibition of toxic epi-dermal necrolysis by blockade of GD95 with human intrave-nous immunogiobulin[ J]. Science, 1998, 282(5388):490-493.
-
6Prins C, Kerdel FA, Padilla RS,et al. Treatment of toxicepidermal necrolysis with high-dose intravenous immunoglob-ulins :multicenter retrospective analysis of 48 consecutivecases[ J]. Archives of dermatology,2003, 139(1):26-32.
-
7Stella M, Clemente A,Bollero D,et al. Toxic epidermalnecrolysis ( TEN) and Stevens-Johnson syndrome ( SJS):experience with high-dose intravenous immunoglobulins andtopical conservative approach. A retrospective analysis [ J }.Journal of International Society for Burn Injuries,2007,33(4) :452-459.
-
8Mockenhaupt M, Viboud C,Dunant A, et al. Stevens-John-son syndrome and toxic epidermal necrolysis : assessment ofmedication risks with emphasis on recently marketed drugs.The EuroSCAR-study[ J ]. Journal of Investigative Dermatol-ogy, 2008,128(1) :35-44.
-
9蔡天国,应雪明.别嘌呤醇致重症药疹9例临床分析[J].中国皮肤性病学杂志,2007,21(9):548-549. 被引量:1
-
10Somkrua R, Eickman EE, Saokaew S, et al. Association ofHLA-B * 5801 allele and allopurinol-induced Stevens Johnsonsyndrome and toxic epidermal necrolysis : a systematic reviewand meta-analysis [ J ]. BMC Medical Genetics, 2011,12:118.
二级参考文献6
-
1Farquhanson CA,Butler R,Hill A,et al.Allopurinol improves endothelial dysfunction in chronic heart failure[J].Ciculation,2002,106(2):221-226.
-
2Hamoka H,Mazatani H,Nouchi N,et al.Allopurinol hypersensitivity syndrome hypersensitivity to oxypurinol but not allopurinol[J].Clin EXP Dermatol,1998,23(1):32-34.
-
3Sullivan JR,Shear NH.The drug hypersensitivity sydrome:What is the pathogenesis?[J].Arch Dermatol,2001,137(3):357-364.
-
4Hande KR,Noone RM,Stone WJ.Serere allopurinol toxicity.Description and guidelines for prevention in patients with renal insufficiency[J].AMJ.Med,1984,76(1):47-56.
-
5陈磊,潘萌,郑捷.别嘌呤醇所致各型药疹的预后与肾功能的关系[J].中华皮肤科杂志,2000,33(2):102-103. 被引量:54
-
6沈新.56例别嘌呤醇药疹的临床特征回顾性分析[J].上海第二医科大学学报,2002,22(3):288-288. 被引量:13
共引文献6
-
1余妍欣,卢凤艳,尹逊国.CO_2激光联合洁悠神抗菌喷剂治疗尖锐湿疣疗效观察[J].皮肤病与性病,2012,34(1):54-54.
-
2方治翔,何咏,邓列华.糠酸莫米松乳膏联合复方甘草酸苷片治疗慢性湿疹临床近期疗效观察[J].中国医药科学,2014,4(6):104-106. 被引量:11
-
3周小花,陈文颖,许功军,黄池清,赵贤伍.皮肤结核86例临床观察及病理分析[J].中国中西医结合皮肤性病学杂志,2015,14(1):49-50. 被引量:1
-
4戴明,胡荣毅,周小勇.早期类似丹毒的皮肌炎1例[J].皮肤病与性病,2015,37(6):356-357. 被引量:1
-
5刘芝伯,关小红.养肝补肾生发汤加减治疗斑秃66例疗效观察[J].中医药临床杂志,2016,28(9):1307-1309. 被引量:2
-
6周爱珍.穴位埋线治疗慢性荨麻疹38例[J].四川中医,2016,34(10):199-200. 被引量:5
同被引文献39
-
1黄玉斌.381例别嘌醇不良反应分析[J].中国药物应用与监测,2005,2(1):32-34. 被引量:23
-
2宋薇,刘精东.高尿酸血症和痛风的流行病学及影响因素研究进展[J].江西医药,2013,48(5):459-462. 被引量:49
-
3干皆诚,庄宣,姚志荣,张定国.47例别嘌呤醇药疹临床及预后分析[J].皮肤病与性病,2007,29(3):6-7. 被引量:3
-
4ROUJEAU J C, STERN R S. Severe adverse cutaneous reactions to drugs [J]. N Engl J Med, 1994,331 ( 19) : 1272- 1285.
-
5SOMKRUA R, EICKMAN E E, SAOKAE S, et al. Association of HLA-B * 5801 allele and allopurinol-induced Stevens Johnson syndrome and toxic epidermal necrolysis . a systematic review and Meta-analysis [J] . BMC Med Genet, 2011 ,12: 118-127.
-
6GERULL R, NELLE M, SCHAIBLE T. Toxic epidermal necrolysis and Stevens-Johnson: a review [J]. Crit Care Med,2011 ,39(6) :1521-1532.
-
7ARELLANO F, SACRISTAN J A. Allopurinol hypersensitivity syndrome: a review [J] . Ann Pharmacother, 1993 , 27(3) :337-343.
-
8ROUJEAU J C. Clinical heterogeneity of drug hypersensitivity[J]. Toxicology ,2005,209(2) : 123-129.
-
9HUNG S I, CHUNG W H, LIOU L B, et al. HLA-B * 5801 allele as a genetic marker for severe cutaneous adverse reactions caused by allopurinol [J]. Proc Natl Acad Sci USA,2005 ,102(11) :4134-4139.
-
10TASSANEEYAKUL W,JANTARAROUNGTONG T,CHEN P, et al. Strong association between HLA-B * 5801 and allopurinol-induced Stevens-Johnson syndrome and toxic epidermal necrolysis in a Thai population [J]. Pharmacogenet Genomics, 2009 , 19 ( 9) : 704 - 709.
引证文献3
-
1于迪,高杰.70例别嘌醇引起的严重皮肤不良反应分析[J].医药导报,2015,34(4):558-560. 被引量:1
-
2韩梅,葛明,李巍.替吉奥致Stevens—Johnson综合征[J].药物不良反应杂志,2016,18(4):295-296. 被引量:2
-
3信凡雪,吴光华.药师参与1例奥卡西平致儿童Steven-Johnson综合征的治疗分析[J].药物流行病学杂志,2018,27(2):131-133.
二级引证文献3
-
1林琳,金弢,董庆泽,付畅.以肾功能衰竭为首发症状的肾结核四例临床诊治分析[J].结核病与肺部健康杂志,2016,5(3):201-204. 被引量:4
-
2孙鹏鹏,张辉,江毓敏,王敬东,张萌.纳武利尤单抗与替吉奥联用致皮疹和免疫相关性肺炎[J].药物不良反应杂志,2022,24(9):497-499.
-
3严若恬,董正邦,王飞.程序性死亡受体1抑制剂致Stevens-Johnson综合征2例[J].中华皮肤科杂志,2023,56(9):866-867.
-
1付春华,赵淑燕,沈红梅.史蒂文斯-约翰逊综合征1例护理[J].河北医学,2004,10(5):466-468.
-
2阎淑玲,邱丙森.扁平苔藓与肝病[J].国外医学(皮肤性病学分册),1989,15(4):214-217.
-
3李阳,王海棠,宋银枝.史蒂文斯-约翰逊综合征1例报告[J].中国中医急症,2012,21(9):1535-1536. 被引量:2
-
4Tsuruta D.,Matsumura- Oura A.,Ishii M.,李晓莉.角层下脓疱病和Sjgren综合征[J].世界核心医学期刊文摘(皮肤病学分册),2006,0(2):61-62.
-
5何明.一例斯梯芬—约翰逊综合征的治疗与护理[J].天津护理,2002,10(3):140-141.
-
6王复昆,马黎民.复发性生殖器疱疹患者免疫细胞检测分析[J].中国麻风皮肤病杂志,2006,22(8):640-640. 被引量:6
-
7王书义,刘宝省.青霉素引致斯蒂芬——约翰逊综合征1例[J].皮肤病与性病,2002,24(1):45-46.
-
8王妍敏,薛峰,李卫平,郑捷.IL-20在寻常型银屑病患者皮损和PBMC中表达的研究[J].现代免疫学,2004,24(1):52-54. 被引量:2
-
9异维A酸的会引起严重皮肤损害及使用风险[J].中国医药导刊,2010,12(8):1392-1392.
-
10訾鹏(译).苯妥英与磷苯妥英钠的安全研究早期通讯[J].中华医学信息导报,2008,23(24):11-11.