评价经皮给药治疗仪佐治小儿急性下呼吸道感染的临床疗效

Evaluations on clinically curative effects of supplementary treatment with therapeutic instrument administering drug cutaneously on acute lower respiratory infection of children

目的 :评价经皮给药治疗仪佐治小儿急性下呼吸道感染的疗效。方法 :将 1999年 7～ 11月确诊为急性下呼吸道感染的住院患儿随机分成治疗组与对照组 ,比较 2组的 3日显效率和 5日显效率 ;治疗组根据肺部体征的不同分成 3组 : 组以湿口罗音和 (或 )喘鸣音为主 , 组以痰鸣音为主 , 组肺部体征不明显但伴有 X线征 ,比较 3个亚组的 3日疗效。结果 :经皮给药治疗仪佐治小儿急性下呼吸道感染疗效显著 ,2组 3日显效率间比较有显著性差异 (2 4.3%比 12 .2 % ,P<0 .0 1) ,特别是对肺部体征以湿口罗音和 (或 )喘鸣音为主的病例疗效更加明显 (3日显效率为 30 .3% )。结论 :早期使用经皮给药治疗仪佐治小儿急性下呼吸道感染能有效地控制病情 。

Objective:To evaluate the curative effects of supplementary treatment with therapeutic instrument administering drug cutaneously on acute lower respiratory infection(ALRI) of children.Methods:Hospitalized children with ALRI from July to November 1999 were randomly divided into treated group and control group.The markedly effective rates on the third day and fifth day respectively were compared between two groups.According to the differences of pulmonary signs the treated group was divided into three subgroups.Group Ⅰ:moist rales and (or) wheezing;group Ⅱ:sputum rales;group Ⅲ:no obvious pulmonary signs but existing chest Xray changes.The curative effects of these subgroups were compared.Results:The markedly effective rates on the third day between the treated group and control group were significant (24 3% vs.12 2%, P <0 01).The curative effects of supplementary treatment with therapeutic instrument administering drug cutaneously on ALRI of children were very obvious,especially for this kind of patients who mainly had moist rales and (or) wheezing as pulmonary signs (the markedly effective rate on the third day was 30 3%).Conclusions:The supplementary treatment with therapeutic instrument administering drug cutaneously used early for ALRI of children is able to control patients′ condition effectively and shorten the ill course. Key words:acute respiratory infection;drug cutaneous administration;drugfast bacterium;antibiotics;children;integrated traditional Chinese medicine and western medicine therapyation.Methods The urinary iodine was measured by spectrophotometer in 42 healthy subjects and 74 patients with Graves disease.Results The median value of urinary iodine after iodine supplementation were 258.0 μg/24h and 500.0 μg/24h in normal subjects and patients respectively,which were higher than those before iodine supplementation.The value of urinary idoine in 21.5% of normal subjects and 50.0% of patients were over 500.0 μg/24h.Conclusions The iodine deficiency was corrected by the supplementation of iodzed salt,however the intake of iodine was higher among the population in Tianjin,which indicated that iodine might be a risk factor in the pathogenesis of Graves disease.