期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

卵泡液代谢组学研究进展 被引量：3

Progress on follicular fluid metabolomics
下载PDF
导出
摘要 卵泡液作为卵母细胞生长和分化的整体环境,直接或间接影响卵母细胞的生长和发育潜能,研究卵泡液中代谢物质的水平,可以间接反映卵细胞代谢水平。卵泡液代谢组学研究将可能成为临床上选择配子和胚胎的一项重要的非侵害性检测技术。本文从卵泡液代谢物组概况、卵泡液代谢物组与卵母细胞发育、早期卵裂和胚胎质量、妊娠结局几方面作简要综述。 Follicular fluid as the whole environment of oocyte growth and differentiation directly or indirectly affects oocyte growth and development potential. Metabolites qualitative level in follicular fluid can indirectly reveal egg cell metabolism level. Follicular fluid metabolomics research could become an important noninvasive detection technology to choose gamete and embryo. This paper reviews the recent progress in follicular fluid metabolomies from follicular fluid metabolites composition and its relationship with ooeyte quality, early cleavage, embryo quality, pregnancy outcome.
作者 姜晓媛 孙振高 连方 张建伟 张宁
机构地区 山东中医药大学临床学院 山东中医药大学附属医院
出处 《生殖医学杂志》 CAS 2013年第11期888-891,共4页 Journal of Reproductive Medicine
基金 国家自然科学基金资助项目(30672706 81072836) 山东省自然科学基金(专项)项目(2009ZRB14306) 2009年度高校博士点专项科研基金联合资助项目(20093731110006)
关键词 卵泡液代谢组学 卵母细胞质量 早期卵裂 胚胎质量 妊娠结局 Follicular fluid metabolomics Oocyte quality Early cleavage Embryo quality Pregnancy outcome
分类号 R [医药卫生]
  • 相关文献

参考文献18

  • 1Tweeddale H, Notley-McRobb L, Ferenci T. Effect of .slowgrowth on metabolism of Escherichia coli, as revealed byglobal metabolite pool ( " metaboiome ") analysis 匸 JJ. JBacteriol, 1998,180:5109-5116.
  • 2Goodacre R,Vaidyanathan S, Dunn WB, et al. Metabolomic.sby numbers: acquiring and understanding global metabolitedata[J]. Trends Biotechnol, 2004,22 :245-252.
  • 3Nicholson JK,Lindon JC,Holmes E. 4 Metabonomics,:understanding the metabolic responses of living systems topathophysiological stimuli via multivariate statistical analysisof biological NMR spectroscopic data[J]. Xenobiotica, 1999,29:11BM189.
  • 4Deepinder F,Chowdary HT, Agarwal A. Role of metabolomicanalysis of biomarkers in the management of male infertility[J]. Expert Rev Mol Diagn,2007,7 : 351-358.
  • 5RevelH A, Delle Piane L,Casano S,et al. Follicular fluidcontent and oocyte quality;from single biochemical markers tometabolomics[J]. Reprod Biol Endocrinol, 2009 ,7 : 40.
  • 6Pinero-Sagredo E,Nunes S,de Los Santos MJ,et al. NMRmetabolic profile of human follicular fluid[J], NMR Biomed,2010,23:485-495.
  • 7McRae C,Baskind NE, Orsi NM,et al. Metabolic profiling offollicular fluid and plasma from natural cycle in vitrofertilization patients-a pilot study [J], Fertil Steril, 2012, 98:1449-1457.
  • 8Arya BK,Haq AU, Chaudhury K. Oocyte quality reflected byfollicular fluid analysis in poly cystic ovary syndrome(PCOS): a hypothesis based on intermediates of energymetabolismQj]. Med Hypotheses, 2012 ,78 : 475-478.
  • 9Bender K,Walsh S, Evans AC,et al. Metaboliteconcentrations in follicular fluid may explain differences infertility between heifers and lactating cows[J]. Reproduction,2010,139:1047-1055.
  • 10Valckx SD,De Pauw I,De Neubourg D,et al. BMI-relatedmetabolic composition of the follicular fluid of womenundergoing assisted reproductive treatment and theconsequences for oocyte and embryo quality [ J ]. HumReprod, 2012,27:3531-3539.

二级参考文献12

  • 1Margalioth EJ,Ben-Chetrit A,Gal M.Investigation andtreatment of repeated implantation failure following IVF-ET.Hum Reprod,2006,21(12):3036-43.
  • 2Singh R,Sinclair KD.Metabolomics:Approached toassessing oocyte and embryo quality.Theriogenology,2007,68(1):56-62.
  • 3Houghton FD,Hawkhead JA,Humpherson PG,et al.Non-invasive amino acid turnover predicts human embryo devel-opmental capacity.Hum Reprod,2002,17(4):999-1005.
  • 4Brison DR,Houghton FD,Falconer D,et al.Identificationof viable embryos in IVF by non-invasive measurement ofamino acid turnover.Hum Reprod,2004,19(10):2319-24.
  • 5Marhuenda-Egea FC,Martinez-Sabater E,Gonsalvez-Alvarez,et al.A crucial step in assisted reproductiontechnology:human embryo selection using metabolomicevaluation.Fertil Steril,2010,94(2):772-4.
  • 6Sturmey RG,Hawkhead JA,Barker EA,et al.DNA damageand metabolic activity in the preimplantation embryo.Hum Reprod,2009,24(1):81-91.
  • 7Sturmey RG,Bermejo-Alvarez P,Gutierrez-Adan A,et al.Amino acid metabolism of bovine blastocysts:a biomarkerof sex and viability.Mol Reprod Dev,2010,77(3):285-96.
  • 8Baltz JM,Tartia AP.Cell volume regulation in oocytes andearly embryos:connecting physiology to successful culturemedia.Hum Reprod Update,2010,16(2):166-76.
  • 9Lane M,Gardner DK.Mitochondrial malate-aspartateshuttle regulates mouse embryo nutrient consumption.JBiol Chem,2005,280(18):18361-7.
  • 10Humpherson PG,Leese HJ,Sturmey RG.Amino acid me-tabolism of the porcine blastocyst.Theriogenology,2005,64(8):1852-66.

共引文献8

同被引文献28

  • 1付志红,邢福祺.活性氧与女性生殖[J].国外医学（计划生育分册）,2005,24(3):107-109. 被引量：11
  • 2Oyawoye OA, Abdel-Gadir A, Garner A, et al. The interaction between follicular fluid total antioxidant capacity, infertility and early reproductive outcomes during in vitro fertilization [J]. Redox Rep,2009,14;205-213.
  • 3Appasamy M,Jauniaux E, Serhal P, et al. Evaluation of the relationship between follicular fluid oxidative stress, ovarian hormones, and response to gonadotropin stimulation [J]. Fertil Steril, 2008,89 : 912-921.
  • 4Pasqualotto EB, Lara LV, Salvador M, et al. The role of enzymatic antioxidants detected in the follicular fluid and semen of infertile couples undergoing assisted reproduction [J]. Hum Fertil,2009,12:166-171.
  • 5Ce|ik E,Ce|ik O, Kumbak B, et al. A comparative study on oxidative and antioxidative markers of serum and follicular fluid in GnRH agonist and antagonist cycles[J]. J Assist Reprod Genet, 2012,29 : 1175-1183.
  • 6Mori T, Amano T, Shimizu H, et al. Roles of gap junctional of cumulus cells in cytoplasmic maturation of pordne oocytes cultured in vitro[J]. Biol Reprod,2000,62:913-919.
  • 7Das S, Chattopadhyay R, Ghosh S, et al. Reactive oxygen species level in follicular fluid-embryo quality marker in IVF? [J]. Hum Reprod,2006,21:2403-2407.
  • 8Kazemi A, Ramezanzadeh F, Nasr-Esfahani MH, et al. Does dietary fat intake influence ooeyte competence and embryo quality by inducing oxidative stress in follicular fluid? [J]. Iran J Reprod Med,2013,11:1005-1012.
  • 9Celik E,Celik O, Kumbak B, et al. A comparative study on oxidative and antioxidative markers of serum and follicular fluid in GnRH agonist and antagonist cycles [J]. J Assist Reprod Genet, 2012,29 :1175-1183.
  • 10Velthut A,Zilmer M, Zilmer K, et al. Elevated blood plasma antioxidant status is favourable for achieving IVF/ICSI pregnancy[J/OL]. Reprod Biomed Online, 2013,26 : 345-352.

二级引证文献32

生殖医学杂志
2013年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部