摘要原发灶不明转移癌（cancer of unknown prima—ry site，CUP）约占所有恶性肿瘤的3％～5％，预后较差[1-3]。转移癌是指肿瘤细胞从原发部位侵入淋巴管、血管或其他途经被带到它处继续生长，而形成与原发部位肿瘤相同类型的肿瘤。由于肿瘤治疗与原发肿瘤的部位、病理类型、分期等密切相关，因此尽早确定肿瘤的原发部位极其重要。
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