甘肃庆阳地区576例变应性鼻炎患者变应原谱分析

The analysis of the allergens in 576 patients with allergic rhinitis in Qingyang of Gansu Province

目的:了解甘肃庆阳地区变应性鼻炎(AR)患者变应原分布情况,为该地区AR的流行病学研究和防治方案提供依据。方法:采用28种变应原对576例疑似AR患者进行皮肤点刺试验,并比较不同年龄段及不同性别在变应原阳性率方面的差异。结果:480例(83.3%)患者变应原呈阳性反应,阳性率相对较高的变应原依次为艾蒿(73.3%)、大豚草(55.7%)、树Ⅱ(51.7%)、树Ⅰ(48.3%)、粉尘螨(43.3%)及屋尘螨(36.7%),并且阳性率随年龄的增长有明显下降趋势,男女性别组间阳性率无明显差异。结论:艾蒿、大豚草、树Ⅱ是庆阳地区最主要的变应原。

Objective：To investigate the allergens distribution of 576 allergic rhinitis patients in Qingyang,and to provide basic epidemiologic information for the prevention and treatment of allergic rhinitis. Method：Skin prick test was done to all the 576 patients with allergic rhinitis with 28 kinds of allergens. Result： Four hundred and eighty cases（83.3 %）showed positive reaction to at least one allergen of 28 allergens. The most common allergens were Magwort （73.3%） ,Giant Ragweed（55.0%）,Tree H （51. 7%） ,TreeI （48.3%）,Dermatophagoides farinae （43.3 %）and Dermatophagoides pteronyssinus（36.7 % ）. Moreover, the positivity decreased with age. There was no difference between male and female. Conclusion： The study shows that Magwort, Giant ragweed and tree Ⅱ are the most important allergens on Qingyang district.