低血糖脑病56例病因及临床特征分析

The etiology and clinical features of hypoglycemic encephalopathy in 56 cases

目的:探讨低血糖脑病的病因及临床特征。方法:对56例低血糖脑病患者的病因及临床特征进行回顾性分析。结果:56例低血糖脑病患者中,39例与降糖药物应用有关,5例由氟喹诺酮类药物所致,4例系进食不足所致,3例系服用不明成分保健品所致,3例原因不明,2例并发上呼吸道感染;临床主要表现为昏迷、精神异常、癫痫、偏瘫及舞蹈样运动等症状。结论:低血糖脑病病因、临床表现复杂,缺乏特异性表现,临床易误诊;对临床出现中枢神经系统损害的病例,需警惕并发低血糖脑病的可能。

Objective：To investigate the etiology and clinical features of hypoglycemic encephalopathy. Methods： The etiology and clinical features of 56 patients with hypoglycemic encephalopathy were retrospectively analysed. Results： Among 56 patients with hypoglycemic encephalopathy,39 cases were related to hypoglycemic drugs, 5 cases were caused by the fluoroquinolone drugs,4 cases were caused by insufficient food,3 cases were caused by unknown components and health products, the causes of 3 cases were unknown and 2 cases were complicated with upper respiratory tract infection. The clinical features were disturbance of consciousness, insanity, epilepsy, hemiplegia and choreic movement. Conclusions： The etiology and clinical features of hypoglycemia encephalopathy are complicated and lack of specificity, which is ease to misdiagnose. The hypoglycemic encephalopathy in the patients with central nervous system damage should be taken into account.