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三碘甲状腺原氨酸、游离甲状腺素、促甲状腺素与女性不孕的关系 被引量:3

The Relationship of Three Triiodothyronine,Free Thyroxine and Thyrotropin with Infertility
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摘要 目的探讨不孕症妇女TSH、FT3及FT4的水平及其相关性。方法对215例因排卵障碍所致的不孕症妇女(观察组)行甲状腺功能筛查,并与同期行常规身体检查的200例正常妇女(对照组)进行对比。结果观察组妇女FT3、FT4显著低于对照组,而FSH、TGAb、TPOAb水平显著高于对照组(P<0.05)。观察组妇女甲状腺功能异常35例(16.30%),对照组甲状腺异常7例(3.50%),差异有统计学意义(P<0.05)。观察组妇女甲状腺异常者月经紊乱发生率、溢乳症发生率、反复流产发生率显著高于甲状腺正常者(P<0.05)。结论甲状腺激素异常与不孕症有密切的关系,临床应加强对不孕症妇女甲状腺功能的检查,以提高不孕妇女甲状腺异常的检出率。 Objective To investigate the levels of blood TSH, FT3 and FT4) with infertility and their correlation. Methods 215 cases of ovulation disorders of infertility( study group) were screened with thyroid function. 200 cases of normal women( control group) were compared. Results The levels of TSH, FT3, FT4 of study group were lower than those of control group, and the levels of TGAb ,TPOAb were significantly higher than those of control group( P 〈 0.05 ). 35 cases of thyroid dysfunction of obser- vation group( 16.30% ) ,seven cases of thyroid abnormalities in control group( 3.50% ) ,the difference was statistically significant ( P 〈 0.05 ). The patients with abnormal thyroid incidence of menstrual disorders, galactorrhea disease incidence and the incidence of recurrent miscarriage were significantly higher than those of normal thyroid group( P 〈 0.05 ). Conclusion Thyroid hormone abnormalities and infertility were closely related.
作者 姚成莲
出处 《中华全科医学》 2013年第12期1885-1886,共2页 Chinese Journal of General Practice
关键词 不孕症 三碘甲状腺原氨酸 游离甲状腺素 促甲状腺素 Infertility Three triiodothyronine Free thyroxine Thyrotropin
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