胰腺癌相关血清学肿瘤标志物的研究现状(综述)

New progress and research status in serum tumor markers of pancreatic cancer

胰腺癌是消化系统的高度恶性肿瘤,近年来在世界范围内发病率呈逐年上升的趋势。由于胰腺解剖部位的特殊性,胰腺癌的早期诊断非常困难,且手术切除率低,5年生存率仅为5%左右。目前胰腺癌的临床诊断主要依赖于费用昂贵的影像学检查或有创检查。选择无创手段如血清肿瘤标志物筛查可疑患者可以提高胰腺癌的检出效率,降低医疗费用。本文简要综述了胰腺癌血清学肿瘤标志物的研究现状和进展。

Pancreatic cancer is a kind of highly malignant tumor of digestive system. In recent years, the morbidity of pancreatic cancer showed an increasing trend. Due to the particularity of pancreatic anatomy, early diagnosis of pancreatic cancer is very difficult, and the rescctable rate is very low. The 5-year survival rate is only about 5%. At present, the clinical diagnosis of pancreatic cancer mainly rely on expensive imaging or invasive examination. Non-invasive methods such as serum tumor markers in patients with suspected pancreatic cancer screening can improve the efficiency of detection and reduce the medical cost. This paper summarized the research status and progress of serum tumor markers of pancreatic cancer.