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硝酸甘油软膏与利多卡因凝胶在肛门病术后换药镇痛中的应用 被引量:1

Nitroglycerin Ointment and Lidocaine Gel for Postoperative Wound Dressing in Anal Disease
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摘要 为探讨肛门病术后创口换药镇痛的有效方法,将300例肛门病术后患者随机分为治疗A组、治疗B组和对照组各100例。治疗A组换药前创面涂抹硝酸甘油软膏;治疗B组换药前创面涂抹利多卡因凝胶;对照组常规换药,分病种对比观察3组患者疼痛评分、创面愈合时间及不良反应发生情况。结果显示,痔、肛裂术后治疗A组换药使用硝酸甘油软膏各方面指标优于其它两组;肛瘘、肛周脓肿术后治疗B组换药使用利多卡因凝胶各方面指标优于其它两组。结果表明,不同病种术后采用不同的换药前用药可减轻患者痛苦,缩短治疗周期。 This study was to discusS the effective analgesic method for postoperative dressing change in anal disease,300 cases were randomized into treatment group A,treatment group B and control group, 100 cases for each group. Nitroglycerin ointment was applied on the wound surface before dressing change in treatment group A, lidocaine gel in treatment group B, and conventional dressing change to the controls. Pain scores,wound surface healing and adverse reactions were observed in the three groups according to their specific disease condition. The results showed that treatment group A was superior to the other two groups after surgery for hemorrhoids and anal fissure; treatment group B was superior to the other two groups after surgery for anal fistula and perinanal abscess. It is concluded that different ways of wound dressing changes can reduce pain,shorten treatment course in different anal diseases.
出处 《中国肛肠病杂志》 2013年第11期62-63,共2页 Chinese Journal of Coloproctology
关键词 肛门疾病 手术 硝酸甘油软膏 利多卡因凝胶 换药 Anal disease Operation Nitroglycerin ointment Lidocaine gel Dressing change
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  • 1Kukovetz WR, Hoknann S, Wtlrm A, et al. Evidenoe for cycle2 GMP mediated relaxant effects of nitro-compounds in coronary smooth mulscle. Arch Pharmacol, 1979, 310 (1):129-138.
  • 2Rapoport RM, Murad F. Agonist induced endotheliunm- ependent relaxation in rat thooracic aorta may be mediated throlish CGMP. Cire Res, 1983,52 (2) : 352-357.
  • 3Hwang DY,Yoon S, Kim HS, et al. Effect of 0. 2 percent oyceryl trinitrate ointment on wound healing after a hemor- rhoidectomy: results of a randomired, prospective, double- blind, placebo-controlled trial. Dis Colon Rectum, 2003,46 (7) :950-954.

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