腹腔镜与小切口胆囊切除术对患者创伤应激反应影响的临床对比研究

Clinical Comparative Study on the Influence of Laparoscopic Cholecystectomy with Small Incision for Patients with Traumatic Stress Reaction Influence

目的:探讨腹腔镜与小切口胆囊切除术对患者创伤应激反应的影响,为临床提供参考。方法:回顾性分析我院收治的需行胆囊切除术的120例患者的临床资料,其中观察组60例行腹腔镜胆囊切除术,对照组60例行小切口胆囊切除术,对比两组手术前后的应激反应指标(中性粒细胞HSP70、血浆CRP和IL-6)及肝肾生化指标(AST、ALT、TBIL、BUN和SCr)。结果:两组内相比,治疗后所有患者的应激及肝肾指标均优于治疗前(P<0.05);而两组间相比,观察组患者均优于对照组(P<0.05)。结论:运用腹腔镜行胆囊切除术,具有对患者应激反应及肝肾功能影响较小、安全性高等特点,临床上值得推广。

Objective：To study the laparoscopic cholecystectomy with small incision for patients with traumatic stress to influence the reaction,choose the appropriate operation.Methods：Analyzed retrospectively to need to do the cholecystectomy clinical data of 120 cases with, including the observation group sixty routine laparoscopic cholecystectomy,control group sixty routine small incision cholecystectomy,compared to two groups before and after the operation of the stress reaction index （neutrophils HSP70,plasma CRP and IL-6） and liver and kidney biochemical indicators （AST,ALT,TBIL,BUN and SCr）.Results：In the two groups after treatment,compared to all patients with stress and hepatorenal indexes is better than before treatment （P〈0.05）;And compared between the two groups,the observation group were superior to that of patients in control group （P〈0.05）.Conclusion：The laparoscopic cholecystectomy,have to stress reaction and liver/kidney patients with less effect,safety higher characteristic,clinical is worthy to be popularized.