新兵嗜肺军团菌抗原快速检测的临床研究

Clinical Study on the Rapid Detection of Legionella Pneumophila Antigen in Recruit

目的:应用快速检测方法对出现呼吸道症状的新兵行嗜肺军团菌(Legionella pneumophila,LP)抗原检测,对检测结果进行分析。方法:收集北京周边5个营区新兵中出现咳嗽、咳痰、咽痛、鼻塞、流涕等呼吸道症状的309人中段尿液标本,应用胶体金免疫层析法(GICA)检测中段尿LP抗原,分析检测结果。结果:LP抗原阳性率9.6%;南北方籍新兵LP抗原阳性检出率差异无统计学意义(P>0.05);E区LP阳性检出率最高(16.5%),与C区相比差异有统计学意义,其他各营区间阳性检出率差异均无统计学意义;发热与不发热的新兵LP抗原阳性检出率差异无统计学意义(P>0.05)。结论:LP抗原检定卡简便、快速,适合基层单位推广。LP感染在出现呼吸道症状的新兵中不容小视,应重视对LP的临床诊断。

Objective：Detecting and analyzing Legionella pneumophila（LP）in recruits with respiratory symptoms by rapid detection method.Methods：Samples were collected from 398 recruits with cough,sputum,sore throat,nasal congestion,runny nose and other respiratory symptoms in five camps around Beijing.In the study, the antigen of legionella pneumophila of midstream urine was detected by gold immunchromatographic assay（GICA）,in the end,analysising the test results.Results：Positive test rate of antigen of LP was 9.6%. The positive rate of LP in the recruits with respiratory symptoms of different regions and fever or not were no significant difference.The military camp of highest positive rate of LP is E,and the difference of positive rate of LP between E and C has statistical significance,there was no statistical differences in other camps.Conclusion：LP antigen gold rapid screen test card has the characteristics of simple,rapid and for the promotion of grass-roots units.Infection of LP in the respiratory symptoms recruits cannot be overlooked,we should pay attention to the clinical diagnosis of the LP.