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伴有少见及复杂核型的恶性淋巴瘤16例

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摘要 目的 分析非霍奇金淋巴瘤(NHL)的细胞遗传学培养方法和少见及复杂核型的变化情况.方法 NHL患者骨髓标本在植物血凝素(PHA)刺激下培养72 h,G显带方法对其进行核型分析.结果 共检出具有少见及复杂核型患者16例,其中10例为复杂核型,另6例涉及1~2条染色体,同一条染色体在不同患者中发生结构或数量异常.结论 骨髓标本在PHA刺激下行72 h培养的方法可提高异常核型的检出,核型变化尤其是复杂核型对患者预后可能产生的影响值得关注.
作者 郭玉琳
出处 《白血病.淋巴瘤》 CAS 2013年第11期684-685,共2页 Journal of Leukemia & Lymphoma
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