美安颗粒联合氨甲环酸治疗黄褐斑的疗效观察

Observation of the Treatment Effect of Mei An Granule Combined with Tranexamic Acid on Chloasma

目的探讨评价黄褐斑采用美安颗粒与氨甲环酸联合治疗的临床效果。方法该次研究选择的对象均为该院2011年12月—2012年12月收治的黄褐斑患者,按观察组和对照组各50例划分,对照组采用维生素B6、肌苷、维生素C联合治疗,观察组在此基础上,加用美安颗粒联合氨甲环酸治疗。结果观察组50例中,总有效率为96%,对照组总有效率为74%,观察组显著优于对照组,差异有统计学意义(P<0.05)。结论黄褐斑应用美安颗粒联合氨甲环酸治疗,可显著提高临床效果,值得在临床推广应用。

Objective To evaluate the clinical effect of Mei An Granule combined with Tranexamic acid on chloasma. Methods 100 patients with chloasma admitted in our hospital from December, 2011 to December, 2012 were selected and divided into observation group and control group with 50 patients in each. The control group was treated with VB6, inosine and VC. And the observation group was treated with Mei An Granule and Tranexamic acid on the basis of VB6, inosine and VC. Results The total effective rate of observation group and control group were 96% and 74%, and there was statistical difference between the two groups（P 〈 0.05）. Conclusion Mei An Granule combined with Tranexamic acid in the treatment chloasma can improve the clinical effect significantly, which is worthy of clinical application.