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肿瘤抗血管生成治疗研究进展

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摘要 肿瘤的生长和转移有赖于血管生成。抗血管生成治疗以血管内皮细胞为靶向 ,通过对抗肿瘤血管生成 ,切断肿瘤的供养 ,从而遏制肿瘤的生长和转移 ,其方法主要包括抑制或中和血管生成因子、应用血管生成抑制剂和针对特异性标记物应用素或抗体攻击肿瘤血管内皮细胞 ,它具有高效性、特异性、不易产生耐药和毒副作用小等优点。迄今 ,包括Endostatin和Angiostatin在内的多种抗血管生成药物在抗肿瘤实验研究中取得良好效果 ,并已开始走向临床。
作者 周洪语
出处 《中国肿瘤生物治疗杂志》 CAS CSCD 2000年第4期308-310,共3页 Chinese Journal of Cancer Biotherapy
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