准分子激光治疗浅层角膜变性(英文)

Excimer laser phototherapeutic keratectomy for superficial corneal dystrophy

目的 探讨准分子激光PTK治疗多种浅层角膜变性 (SCD)的效果。 方法 用MEL 60准分子激光机对 2 6只SCD眼行PTK治疗 ,随访 6～ 18个月。 结果 术后 4～ 15天角膜上皮完全愈合。 2 4眼 (92 % )的最佳矫正视力提高。其中 3眼 (12 % )提高 8行、6眼 (2 3 % )提高 5行、7眼 (2 7% )提高4行、6眼 (2 3 % )提高 3行、2眼 (8% )提高 2行、2眼无变化。2 0眼术后有远视改变。 结论 PTK治疗SCD安全有效 ,近期成功率高、并发症少 。

ObjectiveTo investigate the effect of excimer laser phototherapeutic keratectomy (PTK) for superficial corneal dystrophy (SCD).MethodsTwenty six eyes with SCD were treated using an excimer laser (MEL 60).Follow up ranged from 6 to 18 months.ResultsCorneal reepithelialization was complete within 4~15 days(mean 7 2 days).Best correct visual acuity(BCVA) improved in 24 eyes(92%) after PTK,of which 3 eyes(12%) gained 8 lines of BCVA,6 eyes(23%)5 lines,7 eyes(27%)4 lines,6 eyes(23%)3 lines,and 2 eyes(8%)2 lines during the follow up period.BCVA remained unchanged in 2 eyes.Among these cases,granular dystrophy,and lattice dystrophy had obvious visual improvement,but Salzmann degeneration and band shaped keratopathy had relatively poor visual improvement.The refraction of 20 eyes had hyperopia shift after the surgery,The mean pre and postoperative central corneal thickness,endothelial density were no significant difference ( P >0 05).ConclusionPTK appears to be safe and benificial in the treatment of SCD.The success rate is very high and complications are rare.