期刊文献+

研究人员发现治疗结肠炎的潜在新方法

下载PDF
导出
摘要 结肠炎的症状包括体重减轻、直肠出血等,遗传、饮食及环境是影响结肠炎发展的重要因素。大约50%的直肠癌是由慢性结肠炎发展而来的,通过控制或预防结肠炎可以降低溃疡性结肠炎患者罹患结直肠癌的可能性。目前,约0.5%的加拿大人患有结肠炎,其中艾伯塔省比其他省的发病率高。
作者 温玉琴
出处 《广东药学院学报》 CAS 2013年第5期521-521,共1页 Academic Journal of Guangdong College of Pharmacy
  • 相关文献

参考文献46

  • 1HOLMES D R,DEHMER G J,KAUL S,et al.ACCF/AHA clopidogrel clinical alert:approaches to the FDA "boxed warning":a report of the American college of cardiology foundation task force on clinical expert consensus documents and the American Heart Association endorsed by the society for cardiovascular angiography and interventions and the society of thoracic surgeons[J].J Am Coll Cardiol,2010,56(4):321-341.
  • 2BANSILAL S,BHATT D L.Clopidogrel resistance-a clear problem with an unclear solution[J].Indian Heart J,2012,64(4):353-355.
  • 3HASAN M S,BASRI H B,HIN L P,et al.Genetic polymorphisms and drug interactions leading to clopidogrel resistance:why the Asian population requires special attention[J].Int J Neurosci,2013,123 (3):143-154.
  • 4BREIER A,GIBALOVA L,SERES M,et al.New insight into p-glycoprotein as a drug target[J].Anticancer Agents Med Chem,2013,13(1):159-170.
  • 5MEGA J L,CLOSE S L,WIVIOTT S D,et al.Genetic variants in ABCB1 and CYP2C19 and cardiovascular outcomes after treatment with clopidogrel and prasugrel in the TRITON-TIMI 38 trial:a pharmacogenetic analysis[J].Lancet,2010,376(9749):1312-1319.
  • 6ZINTZARAS E.Is there evidence to claim or deny association between variants of the multidrug resistance gene (MDR1 or ABCB1) and inflammatory bowel disease[J]Inflamm Bowel Dis,2012,18 (3):562-572.
  • 7HOFFMEYER S,BURK O,von RICHTER O,et al.Functional polymorphisms of the human multidrugresistance gene:multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo[J].Proc Natl Acad Sci USA,2000,97(7):3473-3478.
  • 8CORRELL M,JOHNSON C K,FERRARI G,et al.Mutational analysis clopidogrel resistance and platelet function in patients scheduled for coronary artery bypass grafting[J].Genomics,2013,101(6):313-317.
  • 9WU H,KANG H,LIU Y,et al.Roles of ABCB1 gene polymorphisms and haplotype in susceptibility to breast carcinoma risk and clinical outcomes[J].J Cancer Res Clin Oncol,2012,138 (9):1449-1462.
  • 10TANG X F,WANG J,ZHANG J H,et al.Effect of the CYP2C19 2 and 3 genotypes,ABCB1 C3435T and PON1 Q192R alleles on the pharmacodynamics and adverse clinical events of clopidogrel in Chinese people after percutaneous coronary intervention[J].Eur J Clin Pharmacol,2013,69 (5):1103-1112.

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部