我院糖尿病合并尿路感染病原菌特点及耐药性分析

Pathogen Characteristics and Drug Resistance for Diabetic Patients with Urinary Tract Infection in Our Hospital

目的:通过对糖尿病患者尿路感染病原菌分布特点及耐药性的调查分析,为临床医师治疗糖尿病患者尿路感染提供用药依据。方法:回顾性分析359例糖尿病患者合并尿路感染的临床资料,对患者的标本进行培养、分离和鉴定,并用K-B法进行药敏试验。结果:标本经培养、分离和鉴定共检出281株菌株者,以革兰氏阴性杆菌为主,共223株;革兰氏阳性球菌50株;真菌8株。药敏试验结果提示除万古霉素、利奈唑烷、亚胺培南高度敏感外,其余均出现不同程度的耐药,以青霉素、氨苄西林、第三代头孢菌素和喹诺酮类等尤为严重。结论:糖尿病患者易罹患尿路感染,其病原菌以大肠埃希菌为主,其次为肺炎克雷伯菌、金黄色葡萄球菌、表皮葡萄球菌和真菌,且病原菌耐药性较强,应及早进行预防与控制。

Objective ：To investigate the distribution and drug resistance status of pathogenic bacteria of urinary tract infections in diabetics ,for clinicians providing the treatment basis. Methods：The clinical data collected from 359 cases with diabetics were retrospectively analyzed. The culture, isolation !grid identification of the patients＇ specimens were performed, and drug susceptibility test was carried out by K-B method. Results：Specimenr by training,isolation and identification were detected from 281 strains, mainly were gram-negative bacilli 223 strains; of gram-positive coccus 50 strains of fungi 8 strains, except for vancomycin susceptibility test results indicate, rina thiazole alkanes, imine pei south is highly sensitive, the others all appeared different degrees of drug resistance, to penicillin, ampicillin, cephalosporins and third generation quinolone class particularly serious, etc. Conclusion：The patients with diabetics easily suffer from urinary tract infections. The main pathogenic bacteria were Escherichia coli, followed by klebsiella pneumoniae, staphylococcus aureus and epidermis staphylococcus aureus and fungi, and pathogen resistance strong, should as soon as possible to prevent and control.