老年冠心病患者血脂水平与肾功能异常的相关性分析

Correlation Analysis of Serum Lipid Level in Patients with Coronary Heart Disease in Elderly Patients with Abnormal Renal Function

目的:探讨老年冠心病患者血脂水平与肾功能异常的相关性。方法:根据冠状动脉造影结果,将126例老年冠心病患者分为观察A组(1支组,n=52)、观察B组(2支组,n=61)、观察C组(3支组,n=13)。同时选择120例健康体检者作为对照组,比较其血脂水平与肌酐清除率。结果:观察组的HLD-C、ApoA1及CCr低于对照组,ApoB高于对照组,两组比较有显著性差异(P<0.01);各观察组间的HLD-C、ApoA1、ApoB及CCr比较有显著性差异(P<0.05)。结论:冠状动脉的病变程度与肾功能的损害程度密切相关。

Objective：To explore the correlation between blood lipid levels in patients with coronary heart disease in elderly patients with abnormal renal function.Methods：According to the results of coronary angiography, 126 cases of elderly patients with coronary heart disease were divided into A group（1, n=52）, was observed in the B group（2, n=61）, was observed in the C group（3, n=13）. At the same time, 120 healthy subjects served as control group, to compare the levels of lipid and creatinine clearance rate.Results：The observation group HLD-C, ApoA1 and CCr lower than that of the control group, ApoB was higher than the control group, there was significant difference between the two groups（P〈0.01）; there was a significant difference between the groups of HLD-C, ApoA1, ApoB and CCr（P〈0.05）. Conclusions：The extent of the damage degree of coronary artery disease and renal function is closely related.