持续正压通气治疗54例小儿重症毛细支气管炎的临床观察

Clinical Observation of Using Continuous Positive Airway Pressure to Treat 54 Cases of Children Severe Capillary Bronchitis

目的:观察持续正压通气治疗小儿重症毛细支气管炎的临床疗效。方法:小儿重症毛细支气管炎患者108例,通过计算机随机分组的方式将其分为实验组和对照组,每组均为54例。对照组给予常规治疗并给予经鼻导管吸氧,而实验组给予常规治疗并结合鼻塞式的持续正压通气,对比两组患者治疗2h后的血气分析值变化、治疗8d后的总体治疗效果及治疗过程中患儿喘憋消失所需时间、发生并发症的比例。结果:治疗2h后实验组患者的pH值、动脉氧分压均要显著高于对照组(P<0.05)、而实验组患者的二氧化碳分压要显著小于对照组(P<0.05);实验组治疗8d后其总体治疗有效率也要显著高于对照组(P<0.05);治疗过程中实验组患者的喘憋消失所需时间、发生并发症的比例也要显著小于对照组(P<0.05)。结论:持续正压通气治疗小儿重症毛细支气管炎疗效显著,安全性高。

Objective：To observe clinical curative effect of using continuous positive airway pressure to treat children severe capil ary bronchitis. Methods：Chose 108 cases of these children severe capil ary bronchitis patients who have been treated at our hospital from 2009 to 2012,divided them into experimental group and control group according to computer random grouping method,each group has 54 cases;Gave conventional treatment and nasal catheter oxygen to control group＆#39;s patients,while gave conventional treatment combined with nasal continuous positive airway pressure to treat experimental group＆#39;s patients,compared these two groups＆#39; patients＆#39; changes of sap analysis value after 2h of treatment,and their overal treatment effects after 8d of treatment,and children patients＆#39; dyspnea disappearance time and happening rate of complications.Results：Experimental group＆#39;s PH values and pao2 were obviously higher than control group＆#39;s patients＆#39; after 2h of treatment（P〈0.05）,and their partial pressure of carbon dioxide was evidently lower than control group＆#39;s（P〈0.05）;Experimental group＆#39;s overal treatment effective rate was significantly higher than control group＆#39;s（P〈0.05） after 8d of treatment;During the treatment process,experimental group＆#39;s patients＆#39; dyspnea disappearance time and happening rate of complications were significantly less than control group＆#39;s（P〈0.05）.Conclusions：Continuous positive airway pressure has significant curative effect on the treatment of children severe capil ary bronchitis,and it has high security.