血液病房患者合并医院感染临床观察

Clinical Observation of Hospital Infection in Patients with Hematological Ward

目的:探讨血液病房患者医院感染特征及预防。方法:选择60例血液病房住院合并医院感染患者,观察医院感染发病状况、病原体、相关因素及医院感染对预后的影响。结果:医院感染下呼吸道为主25例;送检50份检出病原体38株,革兰阴性杆菌26例,革兰阳性杆菌15例,真菌9例;位于前三位的病原菌是肺炎克雷伯菌伯菌、大肠埃希菌、铜绿假单胞菌。医院感染组患者年龄≥60岁、实施侵入性操作、进行化疗、预防应用抗生素高于无医院感染组(P<0.05),是医院感染相关因素。医院感染患者住院时间、死亡高于同期血液科病房(P<0.05)。结论:血液病患者发生医院感染部位常见,病原体复杂、影响因素多,对预后有不良影响,应采取积极有效的预防措施避免减少医院感染的发生。

Objective：To explore the characteristics and prevention of nosocomial infection in hematological ward patients. Methods：Hospitalized patients with hospital infection in blood cases 60 as the study object, observe the prevalence of hospital infection, hospital infection pathogens, related factors and the influence on prognosis. Results：The nosocomial infection of lower respiratory tract 25 cases; In the 50 samples were positive 38 strains pathogens, gram-negative bacilli 26 cases,gram positive bacteria15 cases, fungal pathogens 9 cases; the top three is pneumonia bacteria Kleber bacteria, Escherichia coli, Pseudomonas aeruginosa. Hospital infection patients aged over 60 years,the implementation oinvasive operation,chemotherapy higher than that without prophylactic use of antibiotics in nosocomial infection group（P〈0.05）, is the related factors of hospital infection. Inpatients with nosocomial infectiondays, the death higher than the same period in the department of hematology（P〈0.05）. Conclusions： Hospital infection occurred in patients with the common blood disease pathogens conclusion, influence factors complex, have adverse effects on prognosis, should take positive and effective preventive measures to avoid reducing the incidence of nosocomial infection.