后部可逆性脑病综合征临床分析

Clinical Analysis of Posterior Reversible Encephalopathy Syndrome

目的:提高对后部可逆性脑病综合征的认识。方法:分析两例患者的临床、影像表现及治疗转归。结果:两例患者均有免疫相关疾病及用药史,主要表现为急性发作的高血压、头痛及癫痫,头颅MRI提示顶枕部白质为主,较为对称的长T1长T2及FLAIR高信号,病程短者DWI等信号,预后较好。结论:有免疫性疾病基础患者出现急性高血压脑病样表现时要注意结合临床表现,注重影像观察以提高诊断准确性,早期干预以改善预后。

Objective：To improve the knowledge of posterior reversible encephalopathy syndrome. Methods：To analyze the characters of clinical manifestations, neuroimgings and prognosis of 2 cases. Results：Both of the 2 cases had a history of immunological disease or drug use. The main clinical charicteristics are blood hypertention, headache and seisure. Symmetrical abnormal long T1, T2 and high Flair signals are dominant in bilateral temporal and occipital lobes. DWI is normal in the case with shorter history and better prignosis. Conclusions：PRES should always be kept in mind for patients with immunological disorders once acute hypertension crisis-like symptoms appear ao as to improve the prognosis.