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乙醛脱氢酶2对缺血复灌心肌保护的研究进展

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摘要 随着生活水平的提高和生活节奏的加快及社会人口日趋老龄化,心血管疾病的发病率和病死率呈迅速上升趋势.尤其是缺血性心脏病的发生占有极高的比率.因此,寻找有效的治疗方案,预防缺血性心脏病的发生,保护缺血心肌,进而提高心脏病患者的生存率具有较高的临床意义.乙醛脱氢酶2（ALDH2）不仅是一种重要的醛类氧化酶,减轻醛类物质对细胞的氧化损伤,而且是体内重要的氧化应激分子,能够抑制细胞凋亡.近年成为了保护缺血心肌的一个研究热点.本文就对ALDH2在心肌保护方面的研究综述如下.
作者 孙颖
机构地区 山东省枣庄市立医院心电图室
出处 《中国医师进修杂志》 2013年第33期73-75,共3页 Chinese Journal of Postgraduates of Medicine
关键词 乙醛脱氢酶2 心肌保护 缺血复灌 缺血性心脏病 缺血心肌 醛类物质 细胞凋亡 心血管疾病
分类号 R541 [医药卫生—心血管疾病]
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参考文献23

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中国医师进修杂志
2013年 第33期

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