翼状胬肉手术疗效的前瞻性研究

PROSPECTIVE STUDY ON EFFICACY OF PRIMARY PTERYGIUM THAT UNDERWENT SURGERY

目的 比较单纯性翼状胬肉切除、翼状胬肉切除联合丝裂霉素C以及翼状胬肉切除联合游离结膜移植对原发性翼状胬肉的临床疗效和安全性。方法 140例(144眼)翼状胬肉患者随机分为3组,A组44眼行单纯性翼状胬肉切除术,B组52眼行翼状胬肉切除联合丝裂霉素术,C组48眼行翼状胬肉切除联合自体游离结膜移植术。术后随访6~24个月,比较各组术后翼状胬肉复发情况。结果 A组44眼中16眼复发,复发率36.36%;B组52眼中16眼复发,复发率为30.78%;C组48眼中2眼复发,复发率为4.17%。A组与C组复发率比较(x^2=15.122,P<0.05)、B组与C组复发率比较(x^2=11.968,P<0.05)差异均有统计学意义。结论 自体游离结膜移植可有效地降低翼状胬肉术后的复发率,是目前较理想的手术方法。

Objective To compare the safety and efficacy of simple pterygium excision vs mitomycin C （MMC） application and conjunctival autograft for treating primary pterygia. Methods One Results The recurrence rate was 36.36% （ 16 of 44 eyes recurred） in group A,30.78% （ 8 of 52 eyes recurred） in group B, and 4.17% （2 of 48 eyes recurred） in group C, there were significant difference in recurrence rate between group A and group C （ X2 = 15. 122, P 〈 0.05 ） , and also between group B and group C （X2 = 15. 122, P 〈 0.05 ）. Conclusion Conjunctival autograft is an effective treatment for preventing recurrence following pterygium excision.