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胰岛素联合二甲双胍、阿卡波糖对糖尿病合并冠心病患者的胰岛素抵抗、脂代谢紊乱的影响 被引量:12

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摘要 目的观察胰岛素联合二甲双胍、阿卡波糖对糖尿病合并冠心病患者的降糖治疗效果,对胰岛素抵抗、脂代谢紊乱的影响。方法糖尿病合并冠心病患者60例,随机分为对照组与治疗组各30例,在常规治疗冠心病基础上,治疗组给予胰岛素、二甲双胍、阿卡波糖控制血糖,停用其他降糖药物,对照组给予磺脲类降糖药控制血糖,治疗90d,并于治疗前后比较胰岛素抵抗指数、胰岛素敏感指数、糖耐量试验、血脂、血糖、糖化血红蛋白的变化。结果治疗90d后2组空腹血糖、糖化血红蛋白明显下降,治疗组下降更明显,治疗组胰岛素抵抗、血脂明显改善。结论胰岛素联合二甲双胍、阿卡波糖可以改善胰岛素抵抗、脂代谢紊乱,是目前治疗糖尿病合并冠心病的理想方案。
出处 《河北医科大学学报》 CAS 2013年第11期1435-1438,共4页 Journal of Hebei Medical University
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