91 例药品不良反应报告分析

Analysis of 91 cases of adverse drug reaction reports

目的了解本院药品不良反应（ADR）发生的特点及一般规律，为深入开展ADR监测工作及临床合理用药提供依据。方法对本院2004年11月～2013年6月上报至国家ADR监测中心的91例ADR报告进行回顾性分析。结果91例报告中，最易引起ADR的药物为抗感染药（占56．25％）和中药注射液（占17．71％），静脉滴注引起的ADR最多，皮肤及其附件损伤为主要临床表现。结论临床应加强ADR监测，合理用药，降低ADR的发生率。

Objective To understand occurrence characteristics and general laws of adverse drug reaction（ADR） in our hospital,in order to provide the basis for ADR monitoring and clinical rational drug use. Methods The 91 cases of ADR reports which reported to the National Center by our hospital from November 2004 to June 2013 were analyzed retrospectively. Results among the 91 cases reports,the most easily caused ADR were anti-infection drugs（represented 56.25%） and Chinese medicine injection （accounted for 17.71%）,ADR caused by intravenous infusion were the most, skin and its appendages injury were the main clinical manifestations. Conclusion The clinical ADR monitoring should be strengthened,and with rational drug use,so as to reduce the incidence of ADR.