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妊娠中晚期体重管理对妊娠早中期增重过多孕妇妊娠结局的影响 被引量:8

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摘要 目的探讨妊娠中晚期体重管理对妊娠前体重指数正常但妊娠早中期增重过多孕妇妊娠期增重和妊娠结局的影响。方法2010年8月至2011年12月间,妊娠20~24周转诊至南京医科大学附属鼓楼临床医学院行产前保健的妊娠前体重指数正常的单胎孕妇共1271例,纳入研究时增重正常者584例,增重超标者687例。增重超标者根据孕妇是否愿意参加体重管理,分为干预组(417例)和非干预组(270例)。干预组中干预依从性好者298例,干预依从性差者119例。采用方差分析及卡方检验比较各组妊娠期增重及妊娠结局的差异。结果1271例孕妇平均年龄为(27.6±3.0)岁(18-42岁),纳入研究时平均孕周为(24.4±1.6)周(20~29周)。干预依从性好者妊娠期总增重为(16.4±3.1)kg,明显低于干预依从性差组和非干预组[分别为(20.5±2.6)kg和(20.8±2.8)kg],差异有统计学意义(q分别为4.104和4.436,P〈0.01)。尽管干预依从性好组纳入研究后增重低于增重正常组[(5.5±2.3)kg与(8.0±3.4)kg,q=2.541,P〈0.01],但妊娠期总增重还是较增重正常组明显增高[(16.4±3.1)kg与(14.0±3.7)kg,q=2.418,P〈0.01]。干预依从性好组妊娠期高血压及子痫前期发生率为2.3%(7/298),低于干预依从性差组和非干预组[分别为7.6%(9/119)和7.0%(19/270)](X^2分别为6.27和7.13,P均G0.05),剖宫产率也较低[23.8%(71/298)与33.6%(40/119)和36.7%(99/270),X^2分别为4.17和11.14,P均G0.053。非干预组巨大儿发生率为11.9%(32/270),高于干预依从性好组和增重正常组[分别为6.7%(20/298)和6.5%(38/584),X^2分别为4.50和7.01,P均〈0.05]。结论妊娠中晚期实行体重管理,可有效改善妊娠结局,但需要良好的患者依从性。
出处 《中华围产医学杂志》 CAS 北大核心 2013年第11期692-695,共4页 Chinese Journal of Perinatal Medicine
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