激光血管内照射结合电针治疗血管性痴呆的临床疗效分析

Analysis of Clinical Therapeutic Effects of Intravascular He-Ne Laser Irradiation Combined with Electroacupuncture Treatment of Vascular Dementia

目的 探讨激光血管内照射结合电针治疗血管性痴呆 (vasculardementia ,VD)的作用。方法 将 6 6例VD患者按区组随机法分为激光结合电针组和药物组 (氢化麦角碱 ,DHET) ,每组各 33例。检测治疗前后长谷川痴呆修改量表、社会活动功能调查、日常生活能力、神经功能缺损、脑电图、超氧化物歧化酶、脂质过氧化物、一氧化氮及观察主要症状等的变化情况 ,共 42天。结果 激光结合电针组上述指标的改善较药物组显著 (P <0 0 5～P <0 0 0 1) ,其有效率为 6 9 7% ,而药物组为 2 1 2 %。结论 该法可促进VD患者智能、社会活动功能及日常生活自理能力的康复 ,提高生活质量 ,其近期疗效优于DHET。

Objective To analyze the clinical therapeutic effects of the intravascular He-Ne laser irradiation combined with electroacupuncture treatment of vascular dementia. Methods 66 patients suffering from vascular dementia were randomly divided into two groups, the intravascular He-Ne laser irradiation combined with electroacupuncture group (ILIE, 33 cases) and the medicine group(dihydroergotoxine, DHET. 33 cases). Changes in scoring value of HDS-R(Hasegawa dementia scale), FAQ(Functional activity questionaire), ADL(Ability of daily life), nerve dysfunction score and main symptoms; concentrations of SOD( Superoxide dismutase), LPO(Lipid peroxide), NO(Nitric oxide) and changes in EEG were examined and compared before and after treatment. The course was 42 days. Results The total effective rate was 69 7% in combination treatment group and 21 2% in DHET group. All the above mentioned indices were better improved in combination treatment group than those of DHET group (P<0 05～0 001). Conclusions It suggests that the combination therapy may improve the VD patients in intelligence, functional activity, ability of daily life andquality of life.