摘要
目的:分析宜兴市第二人民医院药品不良反应(ADR)发生的相关因素,为临床合理用药提供参考依据。方法:对2009—2012年我院上报的317例ADR报告分别从患者年龄、药品种类、给药途径、ADR临床表现等方面进行回顾性分析与评价。结果:317例ADR报告中女性略多于男性;老年患者(≥60岁)发生ADR的比例较高(107例,占34.75%);静脉用药引起的ADR最多(267例,占84.23%);引起ADR最多的药物为抗感染药(137例,占52.68%),其次为中药制剂(67例,占21.14%);ADR临床表现主要为皮肤及其附件损害(192例,占60.57%)。结论:应重视ADR监测,加强合理用药意识,避免或减少ADR的发生,保证临床用药安全、有效。
OBJECTIVE ： To analyze the related factors of adverse drug reactions （ADRs） occurred in our hospital to provide references for clinical rational use of drugs. METHODS： A total of 317 ADR cases reported by our hospital from 2009 to 2012 were analyzed retrospectively with regard to age, drug varieties, routes of administration, clinical manifestation of ADR. RESULTS： Of the 317 ADR cases, female showed higher proportion than males; elder patients （ t〉60 years） had higher proportion （ 107 cases, 34. 75% ）, the ADRs were mostly caused by intravenous route of administration （267 cases, 84.23%）, mostly caused by anti-infective drugs （137 cases, 52.68%） and then traditional Chinese medicine （ 67 cases, 21.14% ）, and the ADRs manifested mainly as damage of skin and its appendants （192 cases, 60. 57%）. CONCLUSION： It is important to attach importance to ADR monitoring and enhance awareness on rational use of drugs to avoid or reduce the occurrence of ADR and ensure the safety and effectiveness of clinical medication.
出处
《中国医院用药评价与分析》
2013年第10期946-948,共3页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
分析
监测
合理用药
Adverse drug reactions
Analysis
Monitor
Rational use of drug
