摘要
目的探讨改良封管液在长期性双腔透析导管血透患者中的应用效果。方法将180例使用长期性双腔透析导管行血液透析的患者随机分为实验组和对照组,每组各90例。实验组于透析结束后采用尿激酶10000U+氨苄西林钠1g+肝素50mg+NS,进行封管,对照组于每次透析结束后采用纯肝素50mg+NS进行封管。3个月后观察2组患者导管相关性感染和血栓的发生率。结果3个月后,实验组患者导管相关性感染发生率为0.00%。对照组为8.89%(χ2=6.41,P<0.05);实验组患者血栓的发生率0.00%,对照组为6.67%(χ2=4.31,P<0.05),实验组患者导管相关性感染和血栓发生率均低于对照组。结论改良封管液不仅可以较好地预防导管相关性感染,同时还可以降低血栓的发生率。
Objective To explore the effect of improved sealing liquid in hemodialysis. Methods 180 patients who used double lumen catheter in hemodialysis chronically were randomly divided into control group and intervention group , each group had 90 patients. After hemodialysis, urokinase 10000 unites ＋ ampicillin sodium 1 g ＋ heparin 50 mg＋NS were given to the intervention group to seal catheter , while heparin 50 mg＋NS were given to the control group to seal catheter. Then compared the incidence of catheter-related infections and thrombus between the two groups after 3 months. Resets After 3 months,the incidence of catheter-related infections of the intervention group was 0% while the control group＇s was 8.89% （X2 =6.41 ,P〈0. 05 ）, the incidence of thrombus of the intervention group was 0% while the control group＇s was 6.67 % （ X2 = 4.31, P〈0.05）. The incidence of catheter-related infections and thrombus of the intervention group were lower than those of the control group. Conclusion The improved sealing liquid can prevent catheter-related infections and reduce thrombus.
