平艾合剂治疗41例HIV/AIDS患者临床观察

Clinical Observation on Effect of Pingai Mixture in the Treatment of 41 HIV/AIDS Patients

目的:观察平艾合剂干预对HIV/AIDS患者的临床疗效,阐明中药应用于艾滋病治疗的特点。方法:选择符合纳入标准的41例HIV/AIDS患者,给予相应的平艾合剂方治疗,3个月为1疗程,治疗2个疗程。观察HIV/AIDS患者治疗前后临床症状、体征及CD4+T淋巴细胞的变化,采用SPSS软件进行统计分析。结果:患者治疗后总积分(主要、次要症状及主要体征积分之和)较疗前明显降低(P<0.01)。自汗、盗汗、脱发等症状的单独积分较治疗前明显降低(P<0.05),其它症状、体征指标变化无统计学意义;Karnovsky Score在治疗6个月时与治疗前相比无显著性差异。结论:平艾合剂治疗艾滋病的疗效确切,可改善患者临床症状,并服用安全。

This study was aimed to observe the clinical effect of Pingai Mixture intervention on HIV/AIDS patients in order to clarify the characteristics of Pingai Mixture for AIDS treatment. A total of 41 HIV/AIDS patients who met the inclusion criteria were selected. Pingai Mixture was applied in the treatment. Three months was one treatment course. The treatment was given for two courses. Clinical symptoms, physical signs and changes in CD4＋ lymphocytes of HIV/AIDS patients before and after treatment were observed. The SPSS software was used for statistical analysis. The results showed that the posttreatment total score （primary, secondary symptoms and the main physical sign cred-its） was significantly reduced compared with pretreatment （P 〈 0.01）. The posttreatment spontaneous perspiration, night sweats, hair loss and other symptoms of a separate score was significantly reduced compared with pretreatment （P〈 0.05）. There were no significant changes on other symptoms or physical sign indicators. There was no significant difference in the Karnovsky score after 6-month treatment compared with pretreatment. It was concluded that Pingai Mixture is effective in AIDS treatment. It can improve the clinical symptoms and the administration is safe.