快速静脉注射生理盐水对肾病综合征患者静脉留置针阻塞发生率的影响

Influence of rapid intravenous injection with normal saline on the incidence of intravenous indwelling needle blocking in patients with nephrotic syndrome

目的探讨快速静脉注射生理盐水对肾病综合征患者静脉留置针阻塞发生率的影响分析,为延长临床静脉留置针使用时间提供理论依据。方法选择2012年1—11月收治的肾病综合征水肿患者28例作为对照组,2012年12月至2013年5月收治的肾病综合征水肿患者28例作为研究组,两组均采用5 mL肝素盐水液正压封管。对照组在封管后留置针启用时直接将药液滴入血管内,研究组在封管后留置针启用时用生理盐水快速静脉注射,然后再将药液滴入血管内。比较两组患者静脉留置针阻塞发生率情况。结果研究组静脉留置针阻塞发生率[17.9%(5/28)]低于对照组[60.7%(17/28)],差异有统计学意义(χ2=10.781,P=0.001)。结论封管后留置针启用时快速静脉注射生理盐水可再通留置管路,延长静脉留置时间。

Objective To investigate the effects of rapid intravenous injection with normal saline（NS） on the incidence of intravenous indwelling needle blocking in patients with nephrotic syndrome, and to provide theoretical basis for prolonging the time of intravenous indwelling needle. Methods 28 edema patients with nephritic syndrome （NS） enrolled from January to November 2012 were selected as control group, and 28 edema patients with nephritic syndrome （NS） enrolled from December 2012 to May 2013 were chosen as research group. Both groups all adopted 5 mL heparin saline liquid positive pressure tube seal- ing. After tube sealing, liquid medicine was dropped to veins directly in control group when the needle was enabled ,while the rapid intravenous injection of NS was applied first,the liquid medicine was dropped to veins in research group when the needle was enabled after tube sealing. The incidence of blocking of venous indwelling needle in the two groups were compared. Results The difference of incidence of intravenous indwelling needle blocking between the two groups had statistical difference （X^2= 10.781, P=-0.001 ）. Conclusion After sealing tube, rapid injection of NS when needle was enabled can recanalize indwelling pipeline and extend the venous indwelling time.