甘肃宫颈癌高发区女性HPV及其疫苗认知状况调查

Survey on cognition of HPV vaccine among women living in high prevalence area of cervical cancer in Gansu Province

目的调查甘肃省宫颈癌高发地区陇南市武都区女性对人乳头瘤病毒（HPV）的认知及对HPV疫苗接种的态度情况。方法采用随机整群抽样的方法抽取武都区2个乡，其中符合筛选条件的30—49岁女性1681人，使用问卷调查女性对HPV认知情况和接种HPV疫苗的态度。结果接受调查女性中1585人（94．29％）没有听说过HPV，但有1584人（94．23％）愿意接受HPV疫苗接种；40岁以下人群对HPV疫苗接种的接受程度明显高于40岁以上人群（P〈0．01）；女性对HPV知晓率与所受教育程度和家庭收入呈正相关（P〈0．01）；调查女性不愿意接种HPV疫苗的原因主要是对宫颈癌的风险意识不足；调查人群中有637人愿意接受医疗机构提供的HPV疫苗，972人接受政府提供的，两项合计占总调查人数的95．71％；有74．84％的人希望国家能够负担部分接种HPV疫苗的费用；本次调查女性中有131人（7．79％）HPV检测呈阳性，HPV感染与未感染女性在HPV认知及其疫苗相关态度调查结果基本一致。结论甘肃省陇南市武都区女性缺乏对宫颈癌和HPV的认知，但是对HPV疫苗的信任和接受程度很高，因此急需通过多种方式加强对陇南地区女性宫颈癌相关科普知识的普及以及改善当地居民生活水平。

Objective To investigate the cognition of HPV and HPV vaccine among women living in high preva-lence area of cervical cancer in Wudu District of Longnan City, Gansu Province. Methods The survey on awareness and attitude towards HPV and vaccination were conducted among women from two rural areas of Wudu District. By using cluster sampling method, 1681 women were investigated through questionnaire. Results 94. 29% of the respondents （ 1585 of 1681 ） didn＇ t know about HPV at all, but 94. 23% of them （ 1584 of 1681 ） would like to take HPV vaccine. Cognition of HPV vaccine were statistically different among different age, degree of education and family income groups （ P 〈 0.05 ）. 95.71% of them were willing to accept HPV vaccine supported by medical institutes （n = 637） or government （n = 972）, and 74. 84% of them expected of the charge paid by government. The HPV infection rate in this survey was 131 （7.79%）, no associations were found between infection cases and uninfected. Conclusion The HPV and cervical cancer cognition a- mong women in Wudu District was deficiency, but HPV vaccine were trusted and accepted in local women. It is necessary to improve HPV and cervical cancer related knowledge and the quality of life essentially.