经尿道钬激光膀胱颈口切开联合坦洛新治疗小体积前列腺增生的疗效观察

Transurethral Holmium Laser Incision of Bladder Neck Joint Tam- sulosin to Treat Small-volume Benign Prostate Hyperplasia

目的：探讨经尿道2．1μm波长钬激光膀胱颈口切开联合坦洛新治疗小体积前列腺增生的疗效。方法对2009年8月～2012年12月收治的25例小体积前列腺增生患者，行经尿道2．1μm波长钬激光膀胱颈口切开术，同时术后服用盐酸坦洛新治疗。结果25例患者均顺利完成手术，平均手术时间18min，术后5d拔除尿管后均排尿通畅。治疗后的1周、4周及12周患者的平均国际前列腺症状评分（IPSS）、生活质量评分（QOL）及最大尿流率（Qmax）较治疗前比较差异显著有统计学意义（P＜0．05）。结论采用经尿道2．1μm波长钬激光膀胱颈口切开联合服用盐酸坦洛新治疗小体积前列腺增生效果显著，能够解除患者膀胱出口梗阻（ BOO）症状，改善患者生活质量，具有手术操作简单，患者创伤小，术后恢复快的优点。

Objective To observe the curative efficacy of treatment for small-volume benign prostate hyperplasia （SBPH）by tran-surethral holmium laser incision of bladder neck combined with tamsulosin hydrochloride .Methods Twenty-five cases of SBPH patients ,in our hospital from August,2009 to December,2012,were treated by transurethral holmium laser incision of bladder neck ,and took 0.2mg tam-sulosin hydrochloride once daily after operation .Results Twenty-five patients were successfully completed operation ,and the average time of the operation was 18 min.All patients had got normal voiding after removal of catheter 5 days postoperatively .After treatment of 1 week,4 weeks and 12 weeks,The mean international prostate symptom score （IPSS）,quality of life score（QOL） and the maximum urinary flow rate （Qmax） compared with those before treatment ,the differences were statisticallysignificant （P〈0.05）.Conclusion It could get a better result to treat small-volume benign prostatic hyperplasia by transurethral holmium laser incision of bladder neck combined with tamsulosin hydro -chloride .It can relieve the symptoms of bladder outlet obstruction and improve patient quality of life obviously .It has advantages of technique simplified,fewer traumas and rapid recuperation .