期刊文献+

高血压病与炎症反应相关性的研究进展 被引量:14

Research progress of hypertension and inflammatory response
下载PDF
导出
摘要 越来越多的证据表明,炎症反应与原发性高血压病之间存在相关性。炎症因子会增加高血压病的患病率,并影响高血压病患者的诊断、治疗和预后。因此,采用一种新的治疗途径去干扰炎症反应和氧化应激可能会改善高血压患者的预后,延缓和减少血管并发症的发生。 Increasing evidence suggests that the inflammatory process is closely associated with essential hypertension. Inflammatory markers have been found to be associated with increased risk of hypertension and could be useful tools in the diagnosis of hypertension in the future. Data reviewed here provide evidence that identification of clinically useful indices and development of novel therapeutic approaches to interfering with inflammation and oxidative stress may ameliorate cardiovascular outcomes in hyperten- sion.
作者 吴婷 宗刚军
出处 《心脏杂志》 CAS 2013年第5期606-608,612,共4页 Chinese Heart Journal
关键词 高血压 原发性 炎症反应 hypertension, essential inflammation
  • 相关文献

参考文献19

  • 1MattaceRaso FU,Verwoert GC,Hofman A,et al.Inflammation and incidentisolated systolic hypertension in older adults: the Rotterdam study[J].J Hypertens,2010,28(5):892-895.
  • 2Androulakis E,Tousoulis D,Papageorgiou N,et al.Essential hypertension: Is there a role for inflammatory mechanisms?[J].Cardiol Rev,2009,17(5):216-221.
  • 3Braunersreuther V,Mach F,Steffens S.The specific role of chemokines in atherosclerosis[J].Thromb Haemost,2007,97(5):714-721.
  • 4Rose P,Bond J,Tighe S,et al.Genes overexpressed in cerebral arteries following saltinduced hypertensive disease are regulated by angiotensin II, JunB, and CREB[J].Am J Physiol Heart Circ Physiol,2008,294(2):1075-1085.
  • 5Brown NJ.Aldosterone and vascular inflammation[J].Hypertension,2008,51(2):161-167.
  • 6Amiri F,Ko EA,Javeshghani D,et al.Deleterious combined effects of saltloading and endothelial cell restricted endothelin1 overexpression on blood pressure and vascular function in mice[J].J Hypertens,2010,28(6):1243-1251.
  • 7Schulz E,Gori T,Münzel T.Oxidative stress and endothelial dysfunction in hypertension[J].Hypertens Res,2011,34(6):665-673.
  • 8Touyz RM,Briones AM. Reactive oxygen species and vascular biology:implications in human hypertension[J].Hypertens Res,2011,34(1):5-14.
  • 9Ienhuis HL,Westra J,Smit AJ,et al.AGE and their receptor RAGE in systemic autoimmune diseases:an inflammation propagating factor contributing to accelerated atherosclerosis[J].Autoimmunity,2009,42(4):302-304.
  • 10Ao J,Shao Y,Lai W,et al.Association of polymorphisms in the RAGE gene with serum CRP levels and coronary artery disease in the Chinese Han population[J].J Hum Genet,2010,55(10):668-675.

同被引文献121

引证文献14

二级引证文献92

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部