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创伤后应激障碍与心血管疾病 被引量:3

Post-traumatic stress disorder and cardiovascular diseases
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摘要 创伤后应激障碍(post-traumatic stress disorder,PTSD)普遍存在于经历过重大身体和心理创伤的普通人群以及退伍或现役军人中。目前临床及流行病学研究已经证实,PTSD可增加高血压病、高血脂、肥胖和心血管疾病的患病风险。PTSD主要的作用机制是,交感肾上腺轴兴奋导致儿茶酚胺分泌增加,进而影响心脏、血管和血小板的功能,增加心血管疾病的发生。本文主要综述PTSD与高血压病和其他心血管病危险因素之间的联系,并阐述PTSD与心血管疾病之间的关系。 Post-traumatic stress disorder (PTSD) is general among populations of veterans and military personnel in active service as well as those who have experienced great physical and psychological trauma. Clinical and epidemiological studies have confirmed that the prevalence of PTSD will increase the risk of hypertension, high cholesterol, obesity and cardiovascular diseases. The main mechanism of PTSD is as follows : the sympathetic adrenal axis excitement leads to an increase of catecholamine secretion, thereby affecting the functions of the heart, blood vessels and platelets, and increases the incidence of cardiovas- cular diseases. This article reviews the connection between PTSD and risk factors for hypertension as well as other cardiovascular diseases. It also elaborates the relationship between PTSD and cardiovascular diseases.
出处 《心脏杂志》 CAS 2013年第5期613-615,共3页 Chinese Heart Journal
关键词 创伤后应激障碍 心血管疾病 普通人群 军人 coronary disease populations post-traumatic stress disorder veterans
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参考文献13

  • 1McFarlane AC.The longterm costs of traumatic stress:intertwined physical and psychological consequences[J].World Psychiatry,2010,9(1):3-10.
  • 2侯小玲,赵连友,薛玉生,艾永飞,景晓娟,牛晓琳,赵晓燕,尚福军.高温应激对大鼠心肌血管紧张素Ⅱ的影响及其与心肌p22phox表达的关系[J].心脏杂志,2009,21(3):304-308. 被引量:8
  • 3Boscarino JA.Posttraumatic stress disorder and physical illness. Results from clinical and epidemiologic studies[J].Ann N Y Acad Sci,2004,1032:141-153.
  • 4Kleim B,Wilhelm FH,Glucksman E,et al.Sex differences in heart rate responses to scriptdriven imagery soon after trauma and risk of posttraumatic stress disorder[J].Psychosomatic Med,2010,72(9): 917-924.
  • 5Vidovic A, Grubisicllic M,KozaricKovacic D,et al.Exaggerated platelet reactivity to physiological agonists in war veterans with posttraumatic stressdisorder[J].Psychoneuroendocrinology,2011,36(2):161-172.
  • 6Cohen BE,Marmar C,Ren L,et al.Association of cardiovascular risk factors with mental health diagnoses in Iraq and Afghanistan war veterans using VA health care[J].JAMA,2009,302(5):489-492.
  • 7Kibler JL,Joshi K,Ma M.Hypertension in relation to posttraumatic stress disorder and depression in the US National Comorbidity Survey[J].Behav Med,2009,34(4):125-132.
  • 8O'Toole BI,Catts SV.Trauma,PTSD,and physical health:an epidemiological study of Australian Vietnam veterans[J].J Psychosom Res,2008,64(1):33-40.
  • 9Maia DB,Marmar CR,Mendlowicz MV,et al.Abnormal serum lipid profile in Brazilian police officers with posttraumatic stress disorder[J].J Affect Disord,2008,107(1-3):259-263.
  • 10Boscarino JA.A prospective study of PTSD and earlyage heart disease mortality among Vietnam veterans:implications for surveillance and prevention[J].Psychosomatic Med,2008,70(6):668-676.

二级参考文献11

  • 1刘慧,彭志英.硫代巴比妥酸化学法测定血浆过氧化脂质[J].华西医学,1994,9(3):275-277. 被引量:8
  • 2何丽华,张金良,张颖,王生,叶康平,石红梅,郑小雨,陈斌.高温对大鼠血压及血管活性物质的影响[J].北京大学学报(医学版),2005,37(4):448-448. 被引量:7
  • 3Finnoff JT. Environmental effects on brain function[ J]. Curr Sports Med Rep, 2008, 7( 1 ) :28 -32.
  • 4Zhang HJ, Doctrow SR, Xu L, et al. Redox modulation of the liver with chronic antioxidant enzyme mimetic treatment prevents age-related oxidative damage associated with environmental stress[ J]. FASEB J, 2004, 18(13) :1547 -1549.
  • 5Zuo L, Christofi FL, Wright VP, et al. Intra and extracellular measurement of reactive oxygen species produced during heat stress in diaphragm muscle [ J ]. Am J Physiol Cell Physiol, 2000, 279 ( 4 ) : C1058 - C1066.
  • 6Li JM, Gall NP, Grieve DJ, et al. Activation of NADPH oxidase during progression of cardiac hypertrophy to failure [ J ]. Hypertension, 2002, 40(4):477-484.
  • 7Lassegue B, Griendling KK. Reactive oxygen species in hypertension: an update[J]. Am J ttypertens, 2004, 17(9) :852 -860.
  • 8Touyz RM, Tabet F, Schiffrin EL. Redox-dependent signalling by angiotensin II and vascular remodelling in hypertension[ J]. Clin Exp Pharmacol Physiol, 2003, 30 ( 11 ) :860 -866.
  • 9Griendling KK, Sorescu D, Ushio-Fukai M. NAD(P) H oxidase role in cardiovascular biology and disease[ Jl. Circ Res, 2000, 86 (5) : 494 - 501.
  • 10Hitomi H, Kiyomoto H, Nishiyama A. Angiotensin II and oxidative stress[J]. Curr Opin Cardiol, 2007, 22(4) :311 -315.

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