上海宝山地区60例慢性咳嗽患者生活质量评估

Quality of life in patients with chronic cough

目的评估上海宝山地区慢性咳嗽患者的生活质量。方法选择2010年12月至2012年12月门诊慢性咳嗽患者60例,对照组为60例健康志愿者。慢性咳嗽组完成简明36项健康问卷(short form-36 health survey,SF-36)、莱塞斯特咳嗽量表(Leicester cough questionnaire,LCQ)、对照组完成SF-36评估;48例慢性咳嗽患者经治疗后,再次完成了SF-36、LCQ量表。结果慢性咳嗽患者SF-36总得分低于健康对照组(P<0.001),其中以情感问题导致的角色受限(role-limitations dueto emotional problems,RE)、总体健康(general Health,GH)和躯体健康问题导致的角色受限(role-limitations due to physical health,RP)三个方面最突出。特异性治疗后,慢性咳嗽患者LCQ总分、生理领域、心理领域、社会领域得分较治疗前升高(P均<0.01)。结论慢性咳嗽患者生活质量下降,特异性治疗后,患者生活质量明显改善。

Objective To evaluate the quality of life in patients with chronic cough. Methods Sixty patients with chronic cough referred to our hospital from December 2010 to December 2012, were recruited in the study and 60 healthy subjects were also included as controls. Health related quality of live short form （SF-36） was measured both in patients and controls; the Leicester Cough Questionnaire （LCQ） were measured in patients before and after management of chronic cough. Results Compared to healthy controls, chronic cough patients reported significantly lower scores in SF-36, especially in RE, GH and RP. LCQ were administered in 48 patients who had a specific therapeutic intervntiun, the total and domains scores were significantly increased （P 〈 0. 001 ）. Conclusion Chronic cough is associated with deterioration in patients quality of life, which would be significantly improved after specific therapeutic intervention.