胺碘酮治疗阵发性室上性心动过速56例临床分析

Clinical Analysis of 56 Patients with Paroxysmal Supraventricular Tachycardia Treated by Amiodarone

目的:总结胺碘酮治疗阵发性室上性心动过速的临床疗效及副作用。方法:回顾性分析2010年1月至2012年12月我科收治的阵发性室上性心动过速患者56例的临床资料,56例阵发性室上性心动过速患者均为临床诊断,胺碘酮采取静脉应用,负荷量(150 mg)加维持量(1 mg/min),首次给药后15-20 min未复律者,再给予负荷量150 mg,负荷总量小于500 mg,2小时后进行疗效和副作用判断。结果:本组56例患者中,1小时内复律21例(37.5%),2小时内复律49例(87.5%),无效7例(12.5%);出现低血压3例(5.4%),恶心2例(3.6%),浅静脉炎1例(1.8%),均无需特殊处理。结论:胺碘酮静脉应用治疗阵发性室上性心动过速疗效显著,副作用少,值得临床推广应用。

Objective：To summarize the clinical efficiency and side effects of patients with paroxysmal supraventricular tachycardia treated by Amiodarone. Method： The clinical data of 56 patients with paroxysmal supraventricular tachycardia were analyzed retrospectively from Jan 2010 to Dec 2012. All of the cases diagnosed as paroxysmal supraventricular tachycardia were bases on clinical and treated by Amiodarone. Amiodarone was used 150 mg intravenous injection as the load dose plus 1 mg/min continuously intravenous infusion to maintain. For the first time ＇after the load dose 150 mg administration of 15-20 min,the load dose 150 mg was given again if not cardioversion, and total load dose was less than 500 mg of Amiodarone. The clinical efficiency and side effects were evaluated after the treatment 2 hs. Results： Among the 56 cases, 21 cases （37.5%） were cardioversion in lh, 49 cases （87.5%） were cardioversion in 2hs, and 7 cases （12.5%） were not cardioversion in 2 hs, 3 cases （5.4%） were hypotension, 2 cases （3.6%） were nausea and l cases （1.8%） was superficial phlebitis. The side effects were not treated specially. Conclusions： It is remarkable clinical effect and no obviously side effects of patients with paroxysmal supraventricular tachycardia treated by Amiodarone used intravenously, and it is worthy of clinical application.