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瞬时受体电位香草酸亚型1在炎症中的作用 被引量：2

Roles of transient receptor potential vanilloid 1 in inflammation
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摘要 瞬时受体电位香草酸亚型1(TRPV1)作为细胞信号的多调受体,可被多种物理、化学因素激活或致敏,从而引起细胞外Ca2+顺电化学梯度向细胞内流动,介导细胞的基本活动,在慢性炎症反应性疾病中发挥重要作用。近年来,研究表明TRPV1具有抑制炎症、保护机体的功能。 As a polytonal receptor of cell signal,transient receptor potential vanilloid 1 （TRPV1） is activated or sensitized by a variety of physical and chemical factors,based on the mode of activation,TRPV1 causes extracellular calcium ion flowing into intracellular cis electric chemogradient,and it mediates basic activities.It plays an important role in chronic inflammatory diseases.In recent years,studies have shown that TRPV1 receptors having the function of inhibit inflammation and protect the body.
作者 赵齐飞 李彬
机构地区 河南中医学院 河南中医学院第一附属医院心病一区
出处 《中国当代医药》 2013年第33期20-21,共2页 China Modern Medicine
关键词 瞬时受体电位香草酸亚型1 炎症 疼痛 Transient receptor potential vanilloid 1 Inflammation Pain
分类号 R364.5 [医药卫生—病理学]
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参考文献21

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同被引文献20

  • 1陈敏,张陆勇,严明.辣椒素受体研究进展[J].中国临床药理学与治疗学,2006,11(2):126-130. 被引量：20
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  • 7Ji RRi Samad TA,Jin SX,et al.p38 MAPK activation by NGF in primary sensory neurons after inflammation increases TRPVl levels and maintains heat hyperalgesia[J].Neuron,2002,36(1):57-68.
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  • 9刘喜德,张金禄,郑汉光,李召东,蔡龙,刘风云,陈滢.蜂针疗法对类风湿关节炎患者外周血TNF-α IL-1β的影响[J].中华中医药学刊,2008,26(5):996-997. 被引量：13
  • 10刘喜德,张金禄,郑汉光,刘风云,陈滢.蜂针疗法治疗类风湿关节炎的临床随机对照研究[J].针刺研究,2008,33(3):197-200. 被引量：29

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中国当代医药
2013年 第33期

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