硫酸吗啡控释片联合认知干预对改善癌性疼痛患者生存质量的影响

目的：评价硫酸吗啡控释片联合认知干预在改善癌性疼痛患者生存质量的有效性。方法对晚期癌症伴有中重度疼痛的患者69例，随机分为联合认知干预组（观察组）33例和单用硫酸吗啡控释片组（对照组）36例；对照组予硫酸吗啡控释片美施康定，观察组在给予美施康定的同时配合认知干预。14d后评价疗效。结果观察组疼痛减轻优于对照组，生存质量量表（SF-36）评分高于对照组。结论对中重度癌性疼痛患者采用硫酸吗啡控释片配合认知干预的综合治疗措施，可以减轻癌性疼痛程度，改善患者生存质量。

Purpose Analysis the effective of changing the life quality by means of Morphine Sulfate Controlled-release Tablets with Cognition Intervene. Methods 69 Patients terminal cancer with moderately sever pain in our oncology department from September,2011 to March,2012. Dividing them randomly into experimental group（n=33）and control group（n=36）. Treated experimental group with morphine sulfate controlled-release tablets（morphine sulfate）. Contrary the control group adds the cognition intervention. After 14 days we evaluate the curative effect. Results The controlling pain of two groups was compared,the differences had statistical significance which showed the experimental group superior to the control group. Considering the grade of life quality table（SF-36）,the experimental group was superior to the control group on multiple aspects and the difference had statistical significance. Conclusion Treating patients who with moderately sever pain by means of morphine sulfate controlled-release tablets and cognition intervention could ease the pain and improve the life quality from several ways. Therefore improving the synthesize effects of patients.