颈围与胰岛素抵抗及心血管疾病风险因素的研究进展

Prospects on Neck Circumference with Insulin Resistance and Cardiovascular Risk Factors

颈围的测量简单易行,立位平视时绕环甲软骨上缘一周的围度。在不同种族、年龄和性别的人群,颈围是上身皮下脂肪蓄积的标志物,颈围增大可作为筛查超重和肥胖、代谢综合征、胰岛素抵抗及心脑血管疾病发生风险的重要参考指标。非酯化脂肪酸水平升高导致身体脂肪的异位分布、亚洲人种的特殊代谢特点及众多脂肪因子发挥的生理和病理效应可能参与其发生机制。在大规模的人群体检及简易的诊室中,通过测定颈围有助于心脑血管事件的早期预防,对改善预后有重要意义。

Neck circumference（ NC ）measurement is simple and can be measured horizontally at the upper margin of the laryngeal prominence when subjects stand with head erect and eyes facing forward. Although varied in races, ages and genders, NC is viewed as an index for upper-body subcutaneous adipose tissue distribution,increasing NC can be an important reference predictor for screening of obesity, metabolic syndrome, insulin resistance and cardiovascular risk factors. Accumulating free fatty acids may result in ectop- ic adipose distribution, also particular Asian ethnic metabolic characteristics and multi-adipocytokines are also involved in the pathological mechanism through different physiological and pathological effects. Measur- ing NC should be used for early stage cardiovascular events prevention in large scale physical examinations and ordinary clinics,which is of great significance for improving the prognosis.