直接进样液相色谱-质谱法测定地表水中的联苯胺

Determination of benzidine in water by liquid chromatography-mass spectrumtry

建立了直接进样液相色谱．质谱法测定水中联苯胺的方法。在优化条件后，方法展示了优异的性能：（a）在0．5—10．0μg·L^-1范围内具有良好的线性关系，相关系数R为0．9999；（b）与其他方法相比，有较低的检出限，仅为0．09μg·L^-1；（c）精密度和准确度较好，相对标准偏差RSD〈5％，空白水样加标回收率在95．8～124％。不同类型的水样和其加标回收率均获得了满意的结果，本方法得以实际应用验证。

An analytical method with liquid chromatography-mass spectrum was developed for the direct determination of benzidine in water. Under optimized eonditions,the method exhibit excellent analytical performance with：（a） good linear relationship ranged from0. 5 to 10. 0μg·L^-1 ,with a correlation coefficient of 0. 9999; （b）lower detection limit comparing to other method, MDL was only 0. 09μg·L^-1;and（c） nice precision and accuracy with RSD〈5% and recovery of blank spike sample ranged from 95.8 to 124% . The applications of the proposed method were validated by analyzing multi-matrix water samples and their spike samples with satisfactory results.