北京市丰台区大气PM10与心血管疾病门诊量关系研究

Relationship between ambient PM10 pollution and daily hospital visits for cardiovascular disease in Fengtai district,Beijing

目的探讨北京市丰台区大气PM10对人群心血管疾病日门诊量的影响。方法采用广义相加泊松回归模型的时间序列研究，在控制门诊量的长期趋势、“星期几效应”、气象因素等混杂因素的影响后，分析北京市丰台区2010年1月1日-12月31日大气PM10日均浓度与心血管疾病日门诊量之间的关系。结果大气PM10浓度每升高10μg／m^3，居民心血管疾病就诊量平均增加0．57％（多因素模型RR=1．0057。95％CI：1．0047-1．0067）。大气PMIO对人群心血管疾病门诊量的影响存在滞后效应，并在滞后第2天（lag2）达到最强。结论本次调查地区的大气PM10浓度与居民心血管疾病门诊量之间存在正向关联。

Objective To explore the relationship between ambient PM10 pollution and daily hospital visits for cardiovascular disease in Fengtai district, Beijing. Methods Generalized additive model （GAM） extended Poisson regression was used to examine the exposure-response relationship between ambient PM10 pollution and daily mortality from January 1, 2010 to December 31, 2010 in Fengtai district, Beijing. Regression analyses was used for the analysis with adjustment for controlling long-term trends, the ＂day of the week＂ effect and meterological factors. Results A 10 μg/m3 increase in PM10 was associated with 0.57% （95%CI：0.47%-0.67%） increase in daily hospital visits for cardiovascular disease. Certain lag effect was observed and the daily hospital visits for cardiovascular disease showed a higher effect at lag 2. Conclusion A positive correlation has been seen between ambient PM10 pollution and daily hospital visits for cardiovascular disease in Fengtai district, Beijing.