摘要
目的 :观察中医药治疗食管疾病及慢性胃病的胃灼热症状临床疗效。方法 :将 2 40例随机分为 3组 ,其中中药辨证论治组 (A组 ) 12 0例 ,按胃热炽盛、胃阴亏虚、脾胃虚寒、寒热虚实挟杂 4个证型处方用药 ,水煎每日 1剂分两次服 ;中药辨证论治加锡类散组 (B组 ) 80例 ,在上述辨证分型处方用药的基础上 ,加用锡类散治疗 ,每次 1支 ,每日 2次 ,2周为 1个疗程 ;对照组 (C组 ) 4 0例 ,服用雷尼替丁 (每次 15 0 mg,每日 2次 ,40 d为 1疗程 )或加服吗丁啉 (每次 10 m g,每日 3次 )。结果 :A、B、C组总有效率为分别 84.2 %、93.8%、42 .5 %。 3组疗效比较 ,A、B两组与 C组之间有非常显著性差异 (P <0 .0 0 1) ,并且 A组与 B组之间差异也较显著 (P <0 .0 5 )。在 A组治疗胃灼热中 ,寒热虚实挟杂证与胃阴亏虚证的疗效有非常显著性差异 (P <0 .0 1) ;在 B组中 ,寒热虚实挟杂证与脾胃虚寒证疗效之间差异非常显著 (P <0 .0 0 1)。结论 :中医药辨证论治治疗食管疾病和慢性胃病胃灼热效果优于西药 ,加用锡类散有助提高疗效。且以寒热虚实挟杂证和胃热炽盛证疗效较好。
Objective:To observe the clinical effect of the Traditional Chinese Medicine in treatment of esophageal diseases and the symptoms of pyrosis with chronic stomach disease.Methods:240 patients were randomly divided into three groups,which were TCM Bianzhenglunzhi group (A group)(120 cases,treated with composit prescription,two times each decoction daily).In accordance with four types of syndrome:excessiveness of stomach heat、deficiency of stomach yin,asthenia of the spleen and stomach and deficiency complicated with excess;BZLZ combined with Xileisan group(B group)(80 cases,treated with TCM and additional XLS,one ampule each time,each twice daily,mertonidazole for 14 days);control group(C group)(40 cases,150 mg ranitidine,each twice daily,mertonidazole for 40 days) or additional motilium Tablets(10 mg,three times a day).Results:The total effective rates of the A group ,the B group the C group were respectively 84.2%,93.8% and 42.5%.With significant difference between the C group and the other two groups(P< 0 01 ),and also markly different between the A group and the B group(P< 0 05 ) .Furthermore,on the treatment of pyrosis in A group,the curative effects had obvious difference between the syndromes of deficiency complicated with excess and deficicency of stomach yin(P< 0 01 );and also presented in B group between the syndromes of deficiency complicated with excess and asthenia of the spleen and stomach(P< 0 001 ).Conclusion:The curative effects of treating pyrosis in A group was significantly superior to that of C group,with XLS given even better result.
