134例肺癌晚期患者的临床特点及预后因素分析

Analysis on clinical characteristics and prognostic factorsin patients with lung cancer

目的：对肺癌患者的临床特点和预后因素进行分析，同时探讨相关的治疗方法。方法：在2010年3月～2013年4月期间，总共收治了肺癌患者134例。对这些患者随机分成对照组和试验组，分别为67例患者；对照组：给患者使用斑蝥酸钠维生素取注射液0．4mg＋0．9％氯化钠注射液250ml进行静脉滴注，一直到患者的病情出现进展或患者对药物的副作用不能忍受为止：试验组：在对照组的基础上，给患者进行临终关怀治疗。对2组患者进行为期6个月的治疗，并对患者进行随访，对在临床上的治疗效果以及出现的不良反应进行评定和对比。结果：试验组治疗总有效率为85．1％明显高于对照组70．1％。差异显著，具有统计学意义（P〈0．05）。预后因素主要有：患者是否吸烟和病理类型以及？临床分期是否有合并症等。结论：对患者的临床特点进行分析和研究，对肺癌患者采用斑蝥酸钠维生素B6注射液联合临终关怀进行治疗，治疗效果显著，且安全性高。

Objective：To analyze the clinical characteristics and prognostic factorsin patients with lung cancer, and to explore therele- vant treatment. Methods：During the period 2010 March -2013 year in April, a total of 134 patients treated with lung cancer. These patients were randomlydivided intocontrol group andexperimental group, respectively 67cases;control group： for patients using disodium cantharidi- nate and vitamin B6 injectionof 0.4mg ＋ 0.9% sodium chloride injection250mlintravenous drip, until disease progression or patients with the side effects of the medieinecan＇t standso far;the test group：in the control group based the patients with ospice care,treatment. Treat- mentfor 6 monthsin twopatients, andthe patients were followed, assessment and comparison of clinical therapeutic effectand adverse reaction of. Results： The treatment group total effective rateof 85.1% was significantly higher than that in control group 70.1%. Significant differences, with statistical significance （ P 〈 0.05 ）. Prognosticfactors were ： whether patientssmokingandpathological type andclinicalcomplica- tions such as the stage. Objectiveto analyse and study theclinical characteristics of the patients, in patients with lung caneerusingdisodium cantharidinate and vitamin B6 injectioncombined withhospice caretreatment mighe have obvious curative effect, high safety andgood effect, prognosis