摘要
目的 :了解医院常见病原菌对喹诺酮类及头孢菌素类抗菌药物的耐药状况 ,指导临床医生选择合适的抗菌药物。方法 :将本医院 1999年 4月— 2 0 0 0年 2月临床分离出的 30 5株常见病原菌对头孢菌素类及喹诺酮类抗菌药物的耐药性进行分析。结果 :喹诺酮类中以环丙沙星抗菌作用仍然较强。常见病原菌中以大肠艾希菌对喹诺酮类抗生素耐药性最高 ;阴沟肠杆菌对头孢菌素类抗生素耐药性最高 ,第三代头孢菌素中 ,头孢他啶耐药率最低 ,头孢曲松耐药率较高 ,头孢噻肟也有所上升 [2 ]。结论 :合理使用抗生素是控制细菌耐药性增长。
Objective:To determine drug resistance of common pathogenic bacteria to quinolone and cephalosporin antibiotics.Methods:We tested the drug resistance of 305 strains of pathogenic bacteria isolated at our hospital.Results:The antibacterial effect of ciprofloxacin was most potent among quinolone antibiotics.The drug resistance of Escherichia coli and Enterobacter cloacae was highest for quinolone antibiotics and cephalosporin antibiotics respectively.Of the third generation of cephalosporin antibiotics,ceftazidine was less drug resistant than both ceftriaxone and cefotaxine.Conclusions:A reasonable use of antibiotics can be critical for the control of drug resistance and iatrogenic infections,as well as the effectiveness of antibiotics.
出处
《现代预防医学》
CAS
2000年第4期526-527,共2页
Modern Preventive Medicine
关键词
病原菌
喹诺酮类
头孢菌素类
耐药率
Pathogenic bacteria
Quinolone antibiotics
Cephalosporin antibiotics
Drug resistance
