摘要
背景:内镜超声引导下细针穿刺活检(EUS—FNA)广泛应用于占位性病变的诊断,但其诊断价值尚未完全明确。目的:评价EUS—FNA对占位性病变的诊断价值。方法:纳入2010年12月~2012年12月于华中科技大学同济医学院附属协和医院就诊的占位性病变患者70例,对占位性病变行EUS—FNA检查,以术后病理诊断作为金标准,评价EUS·FNA的阳性预测值、阴性预测值、敏感性、特异性、准确性以及约登指数。结果:66例患者获得足够细胞或组织学标本,穿刺成功率为94.3%。穿刺成功患者(66例)中,EUS—FNA的阳性预测值、阴性预测值、敏感性、特异性、准确性、约登指数分别为100%、36.4%、88.7%、100%、89.4%和0.887;所有穿刺患者(70例)中,上述数值分别为100%、26.7%、83.3%、100%、84.3%和0.833。所有患者均未发生严重并发症。结论:EUS—FNA对诊断占位性病变安全、有效,具有重要临床价值。
Background: Endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) has been widely used in the diagnosis of space-occupying lesions, however, its diagnostic value is still not fully clear. Aims : To assess the diagnostic value of EUS-FNA on space-occupying lesions. Methods: A total of 70 patients with space-occupying lesions from December 2010 to December 2012 at Wuhan Union Hospital, Tongji Medical College, Huazhong University of Science and Technology were enrolled and had EUS-FNA performed. Postoperative pathology was used as a golden standard. The positive predictive value, negative predictive value, sensitivity, specificity, accuracy and Youden' s index of EUS-FNA were evaluated. Results: Adequate specimen was obtained by EUS-FNA in 66 of the 70 patients, with a successful rate of 94.3%. In 66 patients with adequate specimen, the positive predictive value, negative predictive value, sensitivity, specificity, accuracy and Youden' s index of EUS-FNA were 100% , 36.4% , 88.7% , 100%, 89.4% and 0. 887, respectively, while in all of the 70 patients were 100%, 26.7%, 83.3%, 100%, 84.3% and 0. 833, respectively. No serious complications were found. Conclusions: EUSFNA is a safe and effective diagnostic modality for space-occupying lesions.
出处
《胃肠病学》
2013年第11期676-679,共4页
Chinese Journal of Gastroenterology