白内障术前应用不同浓度聚维酮碘溶液的不良反应观察

Observation on the adverse reactions of different concentrations of povidone- iodine applied before cataract surgery

目的:比较白内障术前应用不同浓度聚维酮碘溶液结膜囊冲洗,术后眼内炎和不良反应发生率,以评价50g/L浓度聚维酮碘溶液预防白内障术后眼内炎的有效性、安全性。方法:将500例白内障手术治疗患者分为50g/L聚维酮碘组和25g/L聚维酮碘组,术中、术后观察眼部体征并询问患者主观不适。结果:50g/L聚维酮碘组眼部刺激症状较25g/L聚维酮碘组明显,但角膜上皮脱失情况和眼内炎的发生两组无区别。结论:术前结膜囊内使用50g/L聚维酮碘溶液是一种有效、安全的预防白内障术后眼内炎的措施。

AIM： To evaluate the efficiency and safety of 50g/L povidone-iodine solution in preventing postoperative endophthalmitis through comparing the incidence of postoperative endophthalmitis and adverse reactions after conjunctival sac washing with povidone -iodine of different concentrations. METHODS： Totally 500 cataract patients were divided into 50g/L povidone-iodine group and 25g/L povidone-iodine group.All the operated eyes were observed during and after surgery.The patients＇subjective discomfort was inquired and their signs of eyes were recorded. RESULTS： The eye irritation of 50g/L povidone-iodine group was more significant than 25g/L povidone-iodine group.No significant difference in the corneal epithelial loss and endophthalmitis was observed between two groups. CONCLUSION： Conjunctival sac washing with 50g/L povidone-iodine is an effective and safe measure to prevent endophthalmitis after cataract surgery.