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骨髓微环境在多发性骨髓瘤发病机制中的作用

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摘要 多发性骨髓瘤(MM)是一种起源于B细胞系的恶性单克隆性浆细胞疾病,临床主要表现为贫血、溶骨性病变、骨痛、免疫缺陷和。肾功能不全。MM的发病机制目前尚不清楚,但其发生发展与骨髓微环境密切相关。骨髓微环境由造血细胞、非造血细胞、细胞外基质、细胞因子等组成。笔者就骨髓微环境在MM发病中的作用及进展进行综述。
出处 《国际输血及血液学杂志》 CAS 2013年第6期537-540,共4页 International Journal of Blood Transfusion and Hematology
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